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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(12): 2036-2046
DOI: https://doi.org/10.20546/ijcmas.2017.612.234


Clinicomicrobial Profile of Neonatal Septicemia at a Tertiary Care Centre in Central India
Purti Tripathi1 and Atul Rukadikar2*
1Department of Microbiology, Government Medical College, Rajnandgaon, Chhattisgarh, India
2Department of Microbiology, Chirayu Medical College, Bhopal, Madhya Pradesh, India
*Corresponding author
Abstract:

Neonatal septicaemia is an important cause of morbidity and mortality among neonates constituting about 30 – 50% of total neonatal deaths in developing countries. Data from various studies reveal that results obtained vary from place to place and from period to period. Early diagnosis and proper management of neonatal septicemia can reduce the morbidity and mortality substantially. 1) To study the bacterial etiologic agents responsible for neonatal sepsis. 2) To study the prevalent bacterial pathogens isolated from early onset neonatal sepsis (EOS) and late onset neonatal sepsis (LOS). 3) To study risk factors associated with neonatal sepsis. 4) To determine the susceptibility pattern of isolates to the commonly used antimicrobial agents in the treatment of sepsis. Blood culture reports were studied in 369 cases of clinically suspected septicemia in neonates using the standard conventional techniques. The antibiotic sensitivity was performed by Kirby-Bauer's disc diffusion method. In our study 66.93% had early onset sepsis and 33.06% had late onset sepsis. Male cases (63.95%) outnumbered female cases (36.04%). Premature rupture of membrane was the most common maternal risk factor (21.95%), while low birth weight was most common neonatal risk factor (70.73%).Blood culture reports were positive in 37.94 % of cases. Klebsiella pneumonia and Enterococcus faecalis were the commonest organisms causing neonatal sepsis in EOS while Pseudomonas aeruginosa and Coagulase negative staphylococcus species in LOS. Continued surveillance of neonatal sepsis should be done in order to follow closely changes in trends and risk factors, to obtain information for empiric antibiotic therapy and to react rapidly in case of major changes in susceptibility patterns and occurrence of outbreaks.


Keywords: Neonatal septicaemia, Antibiotic susceptibility testing
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How to cite this article:

Purti Tripathi and Atul Rukadikar. 2017. Clinicomicrobial Profile of Neonatal Septicemia at a Tertiary Care Centre in Central IndiaInt.J.Curr.Microbiol.App.Sci. 6(12): 2036-2046. doi: https://doi.org/10.20546/ijcmas.2017.612.234