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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(12): 1062-1071
DOI: https://doi.org/10.20546/ijcmas.2017.612.120


Isoflavones: Biosynthesis, Health Promoting Effects and Bioavailability
Sandeep Kumar*
ICAR-IARI, New Delhi-110012, India
*Corresponding author
Abstract:

Isoflavones are one of the various phytochemicals present in soybean considered responsible for its health benefits. Isoflavone come under the class of polyphenolic compounds and are of different chemical forms. In soybean genistein, daidzein and their glycosidic forms are the major isoflavones present. In addition to these small amounts of glycitein and its derivatives are also present. A branch of phenyl propanoid pathway is responsible for isoflavone biosynthesis from simpler precursors. Isoflavone synthase is the key enzyme of this pathway. After action of this enzyme other modifications like glycosylation and malonylation can occur. Due to its structural similarity to estrogens, isoflavones show agnostic and sometimes antagonistic activity, which is considered responsible for anti-cancerous properties of soybean. However, bioavailability is a key factor for bioactivity. The use of microbial fermentation/isolation of efficient hydrolyzing enzymes can make the isoflavones more bioavailable in human digestive system.


Keywords: Biosynthesis, Health, Bioavailability.
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How to cite this article:

Sandeep Kumar. 2017. Isoflavones: Biosynthesis, Health Promoting Effects and Bioavailability.Int.J.Curr.Microbiol.App.Sci. 6(12): 1062-1071. doi: https://doi.org/10.20546/ijcmas.2017.612.120