National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
MicroRNAs are 20–24-nucleotide-long noncoding RNAs that bind to the target mRNAs at the 3′ UTR (untranslated region) and regulate the expression of various oncogenes or tumor suppressor genes. Under various physiological conditions the ability of miRNAs to control gene expression has widely focused and gained their attention. It has also been reported that there is a link between deregulated expression of miRNAs to different disease states. In the last few years there has a great trend to know the biological role of mircoRNA (miRNA) in normal cellular as well as in disease processes. The expression profiling of miRNAs has clearly assessed their role as diagnostic and prognostic biomarkers which will help clinicians to assess tumor initiation, progression and response to treatment in cancer patients. In the development of various stages of cancer, the role and involvement of miRNAs has been revealed. This review focuses on the association of miRNAs with that of cancer and highlights the role of miRNAs in clinical practice, such as diagnosis, prognosis and detection.
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