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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(11): 5373-5384
DOI: https://doi.org/10.20546/ijcmas.2017.611.514


Evaluation of the Antioxidants as Adjunct Therapy in Cattle Naturally Infected with Bovine Tropical Theileriosis
Neelam1*, Naresh Kumar Rakha1, Ricky Jhambh1, Meenakshi Virmani2, Parveen Goel1 and Ramkaran2
1Department of Veterinary Medicine, LLR University of Veterinary and Animal Sciences, Hisar – 125004, Haryana, India
2Department of Veterinary Physiology and Biochemistry, LLR University of Veterinary and Animal Sciences, Hisar – 125004, Haryana, India
*Corresponding author
Abstract:

The present study was planned to evaluate the effect of supplementing non-enzymatic antioxidants as adjunct therapy in enhancing clinical recovery of cattle naturally infected with bovine tropical theileriosis. A total of 18 crossbred dairy cattle with the clinical signs consistent of bovine tropical theileriosis and confirmation by detection of piroplasm infected erythrocytes in blood smears, were randomly divided into 3 groups (A, B, C) of 6 animals each. Animals in group A were treated with specific therapy, buparvaquone @ 2.5 mg/kg intramuscular once; group B treated with vitamin C @ 15 mg/kg intramuscular for nine days along with specific therapy and group C treated with vitamin E @ 1.5 mg/kg plus selenium @ 0.05 mg/kg intramuscular in three doses at three days interval along with specific therapy. The therapeutic evaluation was done on day 0, 3, 6 and 9 of therapy based upon alteration in haemato-biochemical profile and oxidative stress indices. Administration of buparvaquone alone led to disappearance of clinical signs; however, antioxidant supplementation adjunct to specific therapy hastened the clinical recovery. Quicker revival in haemato-biochemical profile was observed in animals of group C which were supplemented with vitamin E-selenium as compared to animals of group B. The oxidative stress indices in blood showed significant improvement in animals which were supplemented with antioxidants; however, more improvement was observed in animals of group C as compare to animals of group B. Thus, the present findings suggest vitamin E-selenium as better adjunct antioxidant therapy than vitamin C in bovine tropical theileriosis.


Keywords: Theileria annulata; bovine tropical theileriosis; vitamin C; vitamin E and selenium; malondialdehyde; glutathione peroxidase; superoxide dismutase
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How to cite this article:

Neelam, Naresh Kumar Rakha, Ricky Jhambh, Meenakshi Virmani, Parveen Goel and Ramkaran. 2017. Evaluation of the Antioxidants as Adjunct Therapy in Cattle Naturally Infected with Bovine Tropical Theileriosis.Int.J.Curr.Microbiol.App.Sci. 6(11): 5373-5384. doi: https://doi.org/10.20546/ijcmas.2017.611.514