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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(11): 1594-1604
DOI: https://doi.org/10.20546/ijcmas.2017.611.191


Detection of ESBLs, MBLs and AmpCs in Gram Negative Uropathogens in Tertiary Care Hospital
Fatima Amatullah*, Gandham Pavani and A.J. Nandeshwar
Department of Microbiology, Maheshwara Medical College, Telangana, India
*Corresponding author
Abstract:

Urinary tract infections are common bacterial infections which vary from asymptomatic bacteriuria to cystitis and pyelonephritis. Infections with multidrug resistant gram negative bacilli have become a great concern as emerging b lactamases like ESBLS, AmpC and MBLs are cause of multidrug resistance in gram negative bacilli. Thus, there detection is needed to prevent UTI and to decrease the hospital stay of patients. Aim of the study is to identify uropathogens causing urinary tract infection. To detect ESBLs, MBLs, AmpC producing isolates from urine. Cross sectional study of 300 urine samples was conducted in Mediciti Institute of Medical Sciences. The samples were processed and gram negative bacilli were identified as per Mackie McCarteny 14th edition. Detection of ESBLs, MBLs and AmpCs producing organisms among the isolates was done by both screening and confirmatory test as per CLSI guidelines. Out of 300 urine samples analyzed, prevalence of gram negative bacilli was 56.6%. The predominant gram negative bacterial isolate was Escherichia coli 55.9%, Klebsiella 26.5% and Pseudomonas 9.4%. Among these isolates 38.8% were ESBL producers, 2.35% MBL producers and 9.4% were AmpC producers. Prevalence of gram negative pathogens in hospital area was 56.6%, predominant isolate was Escherichia coli. ESBLs were the predominant b lactomases produced.


Keywords: ESBL, MBL, AMP C, Carbapenamases, β lactamases.
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How to cite this article:

Fatima Amatullah, Gandham Pavani and Nandeshwar A.J. 2017. Detection of ESBLs, MBLs and AmpCs in Gram Negative Uropathogens in Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 6(11): 1594-1604. doi: https://doi.org/10.20546/ijcmas.2017.611.191