Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(11): 620-627
DOI: https://doi.org/10.20546/ijcmas.2017.611.074


Inflammatory Mediators and Hormonal Changes in Subclinical and Clinically Affected Mastitis Cows
Rachana Sharma*, Manju Ashutosh, Panjab Singh, Sujata Pandita and Mahendra Singh
National Dairy Research Institute (NDRI), Karnal, Haryana 132001, India
*Corresponding author
Abstract:

To investigate the changes that occur in inflammatory mediators and reproductive hormones levels in mastitis crossbred cows, the crossbred cows were screened for SCM incidence (24) by mCMT, SCC, electric conductivity of milk and abnormal milk. Based on this, the cows were divided as group I (n=8) - no clinical symptom of mastitis (healthy), group II (n=8) - showing chronic sub-clinical mastitis (SCM), group III (n=8) - showing clinical mastitis symptoms (CM). Blood samples were collected from group I and II the cows at weekly intervals from day 54 to 138 of lactation. A single blood sample was collected from group III before giving antibiotic treatment. Plasma Nitric Oxide (NO), Interleukin-8 (IL-8), Tumor Necrosis Factor- α (TNF-α), cortisol and prostaglandin (PGFM) levels were higher (P<0.001) in clinical mastitis cows followed by low levels in subclinical mastitis cows. Plasma levels of their parameters were lowest (p<0.001) in healthy cows. Plasma progesterone levels were significantly higher (P<0.001) in healthy cows in comparison to group II and III cows. Plasma TNF-α, PGFM and progesterone levels showed significant (P<0.001) variations between days and between groups I and group II cows whereas NO, IL-8 and cortisol levels did not change.


Keywords: NO, TNF-α, IL-8, Cortisol, Progesterone, PGFM, Subclinical mastitis and Clinical mastitis.
Download this article as Download

How to cite this article:

Rachana Sharma, Manju Ashutosh, Panjab Singh, Sujata Pandita and Mahendra Singh. 2017. Inflammatory Mediators and Hormonal Changes in Subclinical and Clinically Affected Mastitis Cows.Int.J.Curr.Microbiol.App.Sci. 6(11): 620-627. doi: https://doi.org/10.20546/ijcmas.2017.611.074