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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(1): 424-429
DOI: http://dx.doi.org/10.20546/ijcmas.2016.501.042


A Regulatory/ Signaling Molecule of Group A Streptococci (GAS) May be Responsible for Modulation of Bacterial Virulence
Bindu Arora, Anupama Rao and Chinmaya Kashikar
Department of Biotechnology, Abasaheb Garware College, Karve Road, Pune-411 004, India
*Corresponding author
Abstract:

Pathogenic microbes secrete various enzymes to facilitate their survival within the host which may have direct/ indirect role to play in bacterial virulence. In the present work, extracellular amylase producing bacteria were isolated from air, water and soil samples by serial dilution and plating method. Twenty three bacterial isolates obtained were screened for amylolytic activity, out of which only 5 isolates showed amylolytic activity viz: Streptococcus sp., Staphylococcus sp., two Bacillus sp. and Veillonella sp., which were identified by phenotypic characterization. The results revealed that Streptococcus sp. exhibit beta haemolysis on blood agar and had the potential to produce 120 EU extracellular amylase after 48 hours. This is reported here for the first time for production of extracellular amylase. This enzyme might be a regulatory/ signaling molecule and thus be an attractive drug target in the treatment of bacterial infections.


Keywords: Extracellular amylase, Group A Streptococci, Beta haemolysis
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How to cite this article:

Int.J.Curr.Microbiol.App.Sci. 5(1): 424-429. doi: http://dx.doi.org/10.20546/ijcmas.2016.501.042