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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(9): 1807-1811
DOI: https://doi.org/10.20546/ijcmas.2017.609.222


Applications of Myostatin (MSTN) Gene in the Livestock Animals and Humans: A Review
Wani A. Ahad*, Mudasir Andrabi, Sajad A. Beigh, Rumase A. Bhat and Riaz A. Shah
Faculty of Veterinary Sciences and Animal Husbandry, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shuhama Alusteng, India
*Corresponding author
Abstract:

Polymorphism is found in almost all livestock animals including poultry and occurs at all levels of genetic organization from DNA sequence to major morphological traits in livestock animals. Genetic polymorphism contributes to the phenotype variability in animals and is an essential component of genetic improvement of the livestock animals. The genetic variations in livestock animals for meat production create a great interest to the researchers and had been used by them in Marker Assisted Selection (MAS) to identify animals with specific beneficial production traits and there after selecting mating pairs based on these traits. The polymorphism in animals at gene level may arise due to changes in nucleotides. The goal of polymorphism at the gene level is to locate and precisely describe changes in DNA sequences that are responsible for variation among the different phenotypes. Myostatin (MSTN/GDF8) is a member of transforming growth factor-β super family. It is produced by skeletal muscle and acts as a negative regulator of muscle growth. It has an essential role in the regulation of muscle growth and meat quality. As a result, MSTN gene is primarily responsible for muscle growth and development and could be a potential candidate gene marker for animal muscular growth.


Keywords: MSTN, Growth and differentiation factor 8, Double muscling, GDF8, Myostatin.
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How to cite this article:

Wani A. Ahad, Mudasir Andrabi, Sajad A. Beigh, Rumase A. Bhat and Riaz A. Shah. 2017. Applications of Myostatin (MSTN) Gene in the Livestock Animals and Humans:Int.J.Curr.Microbiol.App.Sci. 6(9): 1807-1811. doi: https://doi.org/10.20546/ijcmas.2017.609.222