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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(9): 1653-1600
DOI: https://doi.org/10.20546/ijcmas.2017.609.203


Phytochemical Analysis and Antimalarial Activity of Usnea sp. from South Sulawesi against Plasmodium falciparum
Iwan Dini1*, Maryono1, Akmal2 and Sitti Hajar1
1Chemistry Department, Mathematics and Natural Science, State University of Makassar, Makassar, Indonesia
2Chemistry Laboratory, Mathematics and Natural Science, State University of Makassar, Makassar, Indonesia
*Corresponding author
Abstract:

Usnea sp is known in south Sulawesi as taianging plants. It is one of the kind of lichen species. Local communities in Gowa, south Sulawesi particularly at Malino district were used for medical purposes. The aim of this research is determining the chemical compound of lichen Usnea sp extract and its potential as anti malariai medication. Extracts are obtained by fractional extraction with maceration method using organic solvent. Phytochemical test with chemical reagent and antimalarial potential test through observation of ant plasmodium activity strains of plasmodium falciparum (FCR-3) measured on IC50. The result has shown that Usnea sp extract from Lompobattang mountain contains of alkaloid and saponin compound in methanol extract. In ethyl acetate extract that contains of alkaloid, flavonoid, Quinone and triterpenoid, has showed weak indication. In methanol extract, contains of flavonoid and antarquinon compound. In chloroform extract that contains of saponin, polyphenol, flavonoid antarquinon, triterpenoid and steroid compound. Medium indication in methanol and ethyl acetate extract that contains of polyfhenol compound, strong indication has showed anti plasmodium activity in IC50 for n-hexane, chloroform, ethyl acetate and methanol extract respectively 977.24, 426.58, 5.19 and 3.14 for 24 hours incubation and 32, 36, 22, 23, 3, 74 and 3.42 for 72 hours incubation. This research conclude that the ethyl acetate and methanol extract of Usnea sp contains polyphenol compound with strong indication and both has antimalarial potential as antiplasmodium activity with very good category.


Keywords: Lichenes, Taianging Usnea sp., Phytochemical, Antimalarial, Plasmodium falciparum, Malino, Extraction
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How to cite this article:

Iwan Dini, Maryono, Akmal and Sitti Hajar. 2017. Phytochemical Analysis and Antimalarial Activity of Usnea sp. from South Sulawesi against Plasmodium falciparum.Int.J.Curr.Microbiol.App.Sci. 6(9): 1653-1600. doi: https://doi.org/10.20546/ijcmas.2017.609.203