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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:9, September, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(9): 1206-1210
DOI: https://doi.org/10.20546/ijcmas.2017.609.146


The Effect of Physical Activity on Blood Homocysteine Concentration
Deepak Sinha1 and M.K. Dwivedi2*  
1Department of Chemistry
2Department of Biochemistry Government Nagarjuna PG College of Science, Raipur (CG), India
*Corresponding author
Abstract:

Homocysteine is vasotoxin as well as neurotoxin produced from methionine amino acid in methionine catabolic cycle. Homocysteine mediated generation of free radicals result into inflammation within brain tissues and endothelial membrane. Regular physical activity is essential to maintain homeostasis among biochemical, growth factors, activator proteins and cell signaling pathways and possesses a nourishing impact on regulatory mechanism of body. To identify association we selected 100 case and 223 control, estimated Homocysteine concentration and physical activity. The Chi square value is 25.11 (P<0.0001) and Homocysteine level was significantly low (P<0.0001) in physically active persons 12.19 ± 2.72 µmol/L as compared with inactive 17.27 ± 2.12 µmol/L the t test value was 21.44 (95%CI, 4.61- 5.54). Regular physical activity has found to reduce blood Homocysteine concentration.


Keywords: Homocysteine, Reactive oxygen species, Inflammation, Cardiovascular disease.

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How to cite this article:

Deepak Sinha and Dwivedi, M.K. 2017. The Effect of Physical Activity on Blood Homocysteine ConcentrationInt.J.Curr.Microbiol.App.Sci. 6(9): 1206-1210. doi: https://doi.org/10.20546/ijcmas.2017.609.146
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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