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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(4): 897-903
DOI: http://dx.doi.org/10.20546/ijcmas.2016.504.101


Isolation of Urinary Tract Pathogens and Study of their Drug Susceptibility Patterns
Richa Mishra*, Deepti Saksena and Vinoy K. Shrivastava
Department of Biosciences, Barkatullah University, Bhopal, 462026 (M.P.), India
*Corresponding author
Abstract:

The objective of present study was to analyze urine specimen of patients suffering from UTI for the identification of pathogenic organisms and their drug susceptibility patterns. A total of 1255 (897 females and 358 males) patients with clinical symptoms of UTI were included in the study. Automated bioMérieux VITEK 2 compact bacterial identification and antibiotic susceptibility analyzer is used in the present study. A total of 1255 urine samples were collected and out of these 400 were growth positive isolates. Out of these isolates Escherichia coli (42.5%) was found to be the most frequent causative agent of UTIs followed by Klebsiella spp (23.25%), Pseudomonas spp. (12.5%) and Enterobacter spp.  (9.75%), Candida spp. (5%), Staphylococcus aureus (3%), Acinetobacter spp. (2.5%) and Proteus (1.5%). All urinary isolates of E.coli including multidrug resistant strains were found to be highly sensitive for nitrofuratoin and pazufloxacin. Women are more prone towards UTI and E. coli is the main causative organism. The change in drug susceptibility pattern is notable since older drugs no longer show effectiveness, this is due to resistance developed by overuse or misuse of drugs. Comparative study should be repeated after regular intervals of time so that the changing patterns can be noted and choice of drug can be selected accordingly.


Keywords: Urinary Tract Infections,Drug Resistance, Bacterial Pathogens,E. coli, Antimicrobial Susceptibility Pattern.
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How to cite this article:

Richa Mishra, Deepti Saksena and Vinoy K. Shrivastava. 2016. Isolation of Urinary Tract Pathogens and Study of their Drug Susceptibility PatternsInt.J.Curr.Microbiol.App.Sci. 5(4): 897-903. doi: http://dx.doi.org/10.20546/ijcmas.2016.504.101