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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(8): 3717-3722
DOI: https://doi.org/10.20546/ijcmas.2017.608.449


Seaweed Kappaphycus Extract Proliferation in Mesenchymal Stem Cells and Bread as its Delivery Vehicle
S. Priya1*, V. Perasiriyan2, A. Mangala Gowri3 and K. Ambashankar4
1Department of Food Science and Technology, 2Department of Food Engineering, College of Food and Dairy Technology, Tamil Nadu Veterinary and Animal Sciences University, Chennai- 600 052. Tamil Nadu, India
3Centre for Stem Cell Research and Regenerative Medicine, Tamil Nadu Veterinary and Animal Sciences University, Chennai- 600 007, Tamil Nadu, India
4ICAR- Central Institute of Brackish Water Aquaculture, Chennai, Tamil Nadu, India
*Corresponding author
Abstract:

With the emergence of fortified foods there is a worldwide increase in health alertness and awareness in herbal alternatives. Adoption of fortification techniques enable to enhance the nutritional quality of the product. Common foods such as bread and biscuits can be fortified with enriched herbal extracts. Bread is considered as an excellent source of energy, and an adequate source of protein, essential minerals and other micronutrients. Seaweed, being an untapped source of plant protein and excellent preventive medium against cardiovascular diseases, was enriched in bread at 3, 6 and 9 per cent incorporation level. In vitro studies provide a basis for comparing cytotoxicity data across species. As NRC recommends on the testing the dietary ingredients in target species, herbal extracts were tested in goat bone derived progenitor cells. The herbs at the highest concentration of 100μg/mL tested in proliferation and radical scavenging analysis were found to be safe for use. The seaweed did not show any significant adverse effects on the liveability of cultured cells during the observation period. Supplementation of bread with 3% showed a highest acceptability among the fortified breads. Thus, cereal-based products enriched with seaweed can be used as a vehicle for the delivery of bioactive compounds at suitable levels that provide health benefits for increased well-being. The present study investigated the effect of selected herbs with profound effect to maintain homeostasis in proliferation and radical scavenging activity on tissue progenitor cells.


Keywords: Seaweed, Proliferation, Mesenchymal stem cells, Fortification, Bread
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How to cite this article:

Priya, S., V. Perasiriyan, A. Mangala Gowri and Ambashankar, K. 2017. Seaweed Kappaphycus Extract Proliferation in Mesenchymal Stem Cells and Bread as Its Delivery Vehicle.Int.J.Curr.Microbiol.App.Sci. 6(8): 3717-3722. doi: https://doi.org/10.20546/ijcmas.2017.608.449