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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:4, April, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(4): 825-835
DOI: http://dx.doi.org/10.20546/ijcmas.2016.504.095


Prevalence of Malaria and Typhoid Fever Co-infection among Febrile Patients Attending College of Health Technology Medical Centre in Calabar, Cross River State, Nigeria
Orok, Daniel Archibong1*,Usang, Akedor Ibor1,Ikpan, Ogbe Oyama1,Duke, Edisua E1, Eyo, Emem Efeffiom1, Edadi Ukam Ekup1, Ati2, Boniface Unimke and Udida, Job Akung
1Department of Medical Laboratory Science, College of Health Technology, Calabar, Nigeria
2Department of Biochemistry, Faculty of Basic Medical Sciences, University of Calabar, Calabar, Nigeria
*Corresponding author
Abstract:

A study on prevalence of malaria and typhoid fever co-infection among febrile patients was carried out in College of Health Technology Medical Centre, Calabar, Cross River State, between January and December, 2015. Venepunture technique was used for collection of the blood samples. A total of 250 patients with clinical suspicion of malaria and typhoid fever comprising of 113 males and 137 females were examined. Giemsa stained thick and thin blood films were used to detect malaria parasites in the samples. Typhoid fever was diagnosed from each sample using Widal reagents and cultural method. Out of the 250 patients, 202 (80.8%) tested positive for malaria, 117 (46.8%) tested positive for typhoid by the Widal test and 2 (0.8%) with blood culture. Males 97 (85.8%) were more infected with malaria than females 105 (76.6%) but there was no statistically significant difference (P>0.05) in the prevalence of infection while the prevalence of typhoid fever was higher in females 77 (56.2%) than males 40 (35.4%) and was statistically significant (P<0.05). 70 (28.0%) were co-infected with malaria and typhoid, out of these, 24 (21.2%) were co-infected with malaria and typhoid among the males and 46 (33.8%) were co-infected with malaria and typhoid among the females. Co-infection was highest in the age group of 1 – 15 years in both males and females. The rate of co-infection was high when typhoid fever was diagnosed by Widal (28.0%) than by blood culture method (0.8%). Thus, incidence of typhoid and malaria co-infection will greatly reduce if the diagnosis of typhoid fever in malaria endemic areas such as Calabar is based on blood culture.


Keywords: Typhoid fever,Co-infection, Febrile patients,Calabar

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How to cite this article:

Orok, Daniel Archibong, Usang, Akedor Ibor,Ikpan, Ogbe Oyama, Duke, Edisua E, Eyo, Emem Efeffiom, Edadi Ukam Ekup, Ati, Boniface     Unimke and Udida, Job Akung. 2016. Prevalence of Malaria and Typhoid Fever Co-infection among Febrile Patients Attending College of Health Technology Medical Centre in Calabar, Cross River State, Nigeria.Int.J.Curr.Microbiol.App.Sci. 5(4): 825-835. doi: http://dx.doi.org/10.20546/ijcmas.2016.504.095
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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