National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The revolution of Epigenetics mechanisms including mi-RNA, DNA methylation and histone modification has drawn our attention to target Th17 cell regulatory cytokines and transcription factors which in turn will inhibit the production of interleukin 17 (IL17)- as it’s the key pro-inflammatory cytokine secreted by TH17 cells. The importance of targeting TH17 pathways in autoimmune diabetes come with the deeply ingrained idea of the great role of TH17 in immune pathogenesis of autoimmune diseases. Hepatitis C virus is one of the most common environmental factors which could trigger autoimmune diabetes by inducing local inflammation with cytokine and chemokine secretion (also called “bystander mechanism”.
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