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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 4372-4378
DOI: https://doi.org/10.20546/ijcmas.2017.607.455


Knockdown Therapy for Treatment of Neoplasia in Draught Animals
Govind Mohan1*, P. Satheesh Kumar1, Sushil Kumar1, T.K.Bhattacharya2,Anandasekaran3 and S. Karthiga3
1ICAR-National Dairy Research Institute, Karnal, Haryana-132001, India
2ICAR-Directorate of Poultry Research, Rajendranagar, Hyderabad-500030
3ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh-243122
*Corresponding author
Abstract:

In India more than 50% of the total cultivated area is still being managed by using draught animals. With the modernization of agriculture, the use of tractors has increased but draught animals continue to be used on Indian farms. This mainly due to small land holdings and hill agriculture (G. Singh), India possessed the finest breeds of draught animals. Bullocks, buffaloes and camels are the major draught animals for field operations. Horses, mules, donkeys, yak and mithun are the pack animals for transport. Moreover, India has more number of draught breeds compare to very few milch breeds. The quality of work from the draught animals depends upon the power developed by them. In India draught animals were emotionally attached with the every farmer’s life. Because Draught animals were helping farm works and with several stress condition giving constant Draught Power. Those adverse stress conditions leads to increase the incidence of neoplasia in draught animals which are higher compare to other utility animals in India. There are several factors for neoplasia and the range of neoplasia seen in draught animals is as diverse as that in human. Although more intensive therapeutic interventions, fatality rates remain unacceptably high, moreover not curing of cancerous in animals will be the chance of spread to humans through meat or milk or by direct contact. We are still lagging to solve those therapeutic interventions and fail to prevent the fatal due to neoplasia. Advance therapeutic prevention is therefore an important means of challenging this neoplasia. In this Review, we discuss the advances in the development of knockdown therapy and how we will efficiently utilise to cure the neoplasia in draught animals as well as other domestic animals and human from the Neoplasia.


Keywords: Neoplasia, RNA Interference, knockdown therapy, Sema4D.
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How to cite this article:

Govind Mohan, P. Satheesh Kumar, Sushil Kumar, T.K. Bhattacharya, G. Anandasekaran and Karthiga, S. 2017. Knockdown Therapy for Treatment of Neoplasia in Draught Animals.Int.J.Curr.Microbiol.App.Sci. 6(7): 4372-4378. doi: https://doi.org/10.20546/ijcmas.2017.607.455