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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 2670-2679
DOI: https://doi.org/10.20546/ijcmas.2017.607.376


Investigation of Inhibitory Activity and Bioactive Compounds of Piper nigrum Seeds on Selected Human Pathogens
Renu Chauhan, Ekta Chaudhary and Neha Chauhan*
Division of Life science, Shri Guru Ram Rai Institute of Technology and Science, Dehradun, Uttarakhand, India
*Corresponding author
Abstract:

With the increasing incidents of new and remerging infectious diseases, discovery and urgent need of new microbial compounds having diverse chemical structures and novel mechanism have also been increased. The study focused on determining the antibacterial properties of P. nigrum against pathogenic bacteria and analyzing the phytochemical constituents responsible for these medicinal activities. The plant seeds were collected, shade dried and powdered and subjected to extraction by Cold maceration in various solvents. The extracts were used to determine the antibacterial activity by agar well diffusion method and MIC assay. The phytochemistry was also analyzed. Data obtained showed that the ethyl acetate extract was found to be most effective against the selected bacterial cultures. Phenolic content was found as a major phytochemical constituent. On the basis of the Data obtained it is clear that plant extracts can be used as effective herbal cure against human pathogens.


Keywords: P. nigrum, Cold maceration, Antibacterial activity, Agar-well diffusion, Phytochemicals and MIC.
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How to cite this article:

Renu Chauhan, Ekta Chaudhary and Neha Chauhan. 2017. Investigation of Inhibitory Activity and Bioactive Compounds of Piper nigrum Seeds on Selected Human Pathogens.Int.J.Curr.Microbiol.App.Sci. 6(7): 2670-2679. doi: https://doi.org/10.20546/ijcmas.2017.607.376