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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here
ICV 2022: 95.28
Index Copernicus ICI Journals Master List 2022 - IJCMAS--ICV 2022: 95.28
For more details click here
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Original Research Articles                      Volume : 6, Issue:7, July, 2017
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38
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Int.J.Curr.Microbiol.App.Sci.2017.6(7): 1727-1734
DOI: https://doi.org/10.20546/ijcmas.2017.607.208


Glycoprotein Based Phylogenetic Analysis of Rabies Virus Isolates
Neha R. Tomar1*, Rajiv Kumar2 and Anil Kumar3
1Department of Zoology, Kumaun University, S. S. J. Campus, Almora, Uttarakhand, India
2Division of Animal Genetics and Breeding, C. S. W. R. I., Avikanagar, Rajasthan, India
3Department of Molecular Biology and Genetic Engineering, College of Basic Sciences and Humanities, G. B. Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India
*Corresponding author
Abstract:

Glycoprotein of rabies virus is major contributor to pathogenicity. Glycoprotein based phylogenetic analysis of twenty three rabies and rabies related virus including CVS strain was done by aligning the sequences by clustal W. Glycoprotein sequence based phylogenetic tree was constructed and ten conserved motifs were analyzed among these glycoproteins. The unique sequence of motif 4 was observed only in CVS strain (FJ979833) which might be responsible for discriminating CVS strain from other rabies virus strains. The present study might open the possibility of developing strain specific PCR for identification of rabies virus in canids.


Keywords: Canids, Rabies, Glycoprotein, Phylogeny, Strain specific PCR.

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How to cite this article:

Neha R. Tomar, Rajiv Kumar and Anil Kumar. 2017. Glycoprotein Based Phylogenetic Analysis of Rabies Virus Isolates.Int.J.Curr.Microbiol.App.Sci. 6(7): 1727-1734. doi: https://doi.org/10.20546/ijcmas.2017.607.208
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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