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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 2366-2370
DOI: https://doi.org/10.20546/ijcmas.2017.607.338


Microbial Profile of High Vaginal Swab from Women of Reproductive Age Group in a Tertiary Care Hospital
Anna Cherian* and O. Sasikumari
Department of Microbiology, Govt. Medical College, Trivandrum, Kerala, India
*Corresponding author
Abstract:

Bacterial vaginosis, candidiasis and trichomoniasis, along with sexually transmitted infections are the common vaginal infections in women of reproductive age group in developing countries. Here the normal vaginal flora, consisting of peroxide-producing lactobacilli, are replaced by Gardnerella vaginalis, Mycoplasma hominis, Mobiluncus species, and anaerobic gram-negative rods. 1In the pregnant state microbial infections can lead to premature rupture of membranes which in turn can cause infant morbidity and mortality due to infections. Early detection and appropriate antimicrobial therapy can be life-saving by preventing vertical transmission of the pathogens. To find out the Microbiological profile of high vaginal swabs (HVS) from patients with various lower genital tract symptoms in the reproductive age group, attending the Obstetrics and Gynaecology Department at Sree Avittam Thirunal Hospital (SATH), Thiruvananthapuram, Kerala, South India. A hospital based study was done on 1315 high vaginal swabs collected during a period of two years, from May 2015 to April 2017.The samples were cultured aerobically on Blood agar (BA), Chocolate agar(CA)and Mac Conkey agar(MA) for microbial isolation. The overall positivity for pathogenic aerobic microbes was 234 (18%), while 1081 (82%) grew normal vaginal flora. Candida was the predominant pathogen in 125(53%) patients. In this study there was a significantly high rate of detection of Candida species when compared to bacterial isolates. This justifies the practice of empirical antifungal therapy without taking high vaginal swabs in patients with complaints of vaginal discharge or related symptoms especially in the Gynaecology OPD. The detection of pathogens in HVS culture and its appropriate treatment in symptomatic pregnant women is also necessary for a full term normal pregnancy, child birth and a healthy baby.


Keywords: HVS (high vaginal swab), Vaginal infection, Candidiasis, Aerobic culture, Genital tract pathogens.
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How to cite this article:

Anna Cherian and Sasikumari, O. 2017. Microbial Profile of High Vaginal Swab from Women of Reproductive Age Group in a Tertiary Care HospitalInt.J.Curr.Microbiol.App.Sci. 6(7): 2366-2370. doi: https://doi.org/10.20546/ijcmas.2017.607.338