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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 2188-2193
DOI: https://doi.org/10.20546/ijcmas.2017.607.317


Bacteriological Profile and Anti Microbial Susceptibility Pattern of Neonatal Sepsis in a Tertiary Care Hospital
Meerah Srinivasagam*, Vijayalakshmi Arumugam and Rajeswari Jayakumar
Department of Microbiology, Chengalpattu Medical College, Chengalpattu, Kanchipuram District, Tamilnadu, India
*Corresponding author
Abstract:

Neonatal sepsis refers to systemic and generalized infection of the newborn which is documented by a positive blood culture in the first four weeks of life. It is one of the four leading causes of neonatal mortality in India, to isolate bacterial pathogens in neonates with clinical suspicion of sepsis from blood samples and to study their antimicrobial susceptibility pattern. Blood samples collected from 1072 neonates with suspected sepsis were processed. Out of 1072 neonates 231(21.54%) were culture positive. 122(52.81%) of bacterial pathogens were isolated in early onset sepsis and 109(47.18%) in late onset sepsis. Among the isolated bacteria 126 (54.55%) were Gram negative and 105 (45.45%) were Gram positive. Klebsiella species and Staphylococcus aureus were the predominantly isolated organisms. Anti microbial susceptibility pattern revealed that Piperacillin-Tazobactum and Imepenem were the two most effective antibiotics against Gram negative bacteria and Vancomycin and linezolid still remains the most effective drug for Staphylococcus aureus. In neonatal sepsis knowledge of the commonly isolated organism and their anti- microbial susceptibility pattern in our geographical area, aids in the selection of appropriate antimicrobials for therapy.


Keywords: Early onset sepsis, Late onset sepsis, Pathogens.
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How to cite this article:

Meerah Srinivasagam, Vijayalakshmi Arumugam and Rajeswari Jayakumar. 2017. Bacteriological Profile and Anti Microbial Susceptibility Pattern of Neonatal Sepsis in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 6(7): 2188-2193. doi: https://doi.org/10.20546/ijcmas.2017.607.317