National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Neonatal sepsis refers to systemic and generalized infection of the newborn which is documented by a positive blood culture in the first four weeks of life. It is one of the four leading causes of neonatal mortality in India, to isolate bacterial pathogens in neonates with clinical suspicion of sepsis from blood samples and to study their antimicrobial susceptibility pattern. Blood samples collected from 1072 neonates with suspected sepsis were processed. Out of 1072 neonates 231(21.54%) were culture positive. 122(52.81%) of bacterial pathogens were isolated in early onset sepsis and 109(47.18%) in late onset sepsis. Among the isolated bacteria 126 (54.55%) were Gram negative and 105 (45.45%) were Gram positive. Klebsiella species and Staphylococcus aureus were the predominantly isolated organisms. Anti microbial susceptibility pattern revealed that Piperacillin-Tazobactum and Imepenem were the two most effective antibiotics against Gram negative bacteria and Vancomycin and linezolid still remains the most effective drug for Staphylococcus aureus. In neonatal sepsis knowledge of the commonly isolated organism and their anti- microbial susceptibility pattern in our geographical area, aids in the selection of appropriate antimicrobials for therapy.
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