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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 2288-2294
DOI: https://doi.org/10.20546/ijcmas.2017.607.269


Study of Virulence Factors in Escherichia coli Isolated from Skin and Soft Tissue Infections
R. Saraswati Jayanthi1* and K. Soumya2
1Department of Microbiology, ESIC Medical College, Sanathnagar, Hyderabad, Telangana, India
2Department of Microbiology, Shridevi Institute Of Medical Sciences and Research Hospital, Tumkur, Karnataka, India
*Corresponding author
Abstract:

Escherichia coli are normal commensals of the intestinal tract. But have been implicated to cause urinary tract infections, wound infections, septicaemias and neonatal meningitis. Extra-intestinal pathogenic Escherichia coli (ExPEC), the specialized strains of E coli that cause most extra-intestinal E. coli infections, represent a major but little appreciated health threat. The present study aimed at characterising the extra intestinal pathogenic E. coli (ExPEC) other than UPEC (UropathogenicE. coli) and to correlate their virulence factors with the clinical diagnosis and these with isolates from stool samples. The antibiotic susceptibility pattern in these isolates was also reviewed. The study was conducted at Dept. of Microbiology. 50 consecutive isolates of E. coli from wound swabs or pus collected from skin and soft tissue infections were characterised. These isolates were screened for colony morphology, serum resistance, haemolysin production, gelatin hydrolysis, cell surface hydrophobicity, and haemagglutination, ESBL and antibiotic profile. Out of 50 isolates from SSTI, 6 (12%) were haemolytic, 16 (32 %) formed mucoid colony and 32(68 %) were non mucoid, 16 (32%) were serum resistant, 3 (6 %) produced gelatinase, 12(24%) were hydrophobic, 37 (74%) produced mannose sensitive haemagglutination & 13 (26%) mannose resistant haemagglutination and 80% were multidrug resistant. E. coli is commonly isolated from SSTI but their importance as etiological agents in these infections is questionable. The present study does demonstrates the virulence potential in the E. coli strains isolated from SSTI. There is a need to further study the virulence factors of these ExPEC (Extra intestinal pathogenic E. coli) in more number of isolates and with the use of molecular techniques.


Keywords: SSTI, ExPEC, Virulence factors
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How to cite this article:

Saraswati Jayanthi, R. and Soumya, K. 2017. Study of Virulence Factors in Escherichia coli Isolated from Skin and Soft Tissue Infections.Int.J.Curr.Microbiol.App.Sci. 6(7): 2288-2294. doi: https://doi.org/10.20546/ijcmas.2017.607.269