Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 1416-1420
DOI: https://doi.org/10.20546/ijcmas.2017.607.169


Seroprevalence of Hepatitis C Virus Infection among Chronic Kidney Disease Patients on Maintenance Hemodialysis in a Tertiary Care Hospital
Nirmaladevi Somsundaram* and R. Vidhya Rani
Department of Microbiology, Government Mohan kumaramangalam Medial College, Salem, Tamil Nadu, India
*Corresponding author
Abstract:

HCV is a major cause of increased morbidity and mortality in patients with chronic kidney disease (CKD). Since, HCV is transmitted through blood and blood products prevalence of anti-HCV among Hemodialysis (HD) patients is consistently higher among them. Factors such as blood transfusion and frequent parenteral interventions have been shown to be associated with increased risk of HCV infection. A total of 107 blood samples were collected from CKD patients on maintenance hemodialysis in a tertiary care hospital and the sera separated, stored at -20° C and tested for anti-HCV antibodies by using third generation ELISA. Out of 107 CKD Patients 33 (30.8%) were positive for anti-HCV, of 33 seropositives 21 (63.6 %) were males and 12 (36.4%) were females. 19 (57.6%) out of 33 seropositives had received multiple blood transfusions and prevalence of HCV was higher among (75.7%) those patients who had undergone increased duration and number of hemodialysis. Hemodialysis patients should be routinely screened for HCV infection, preferably using serological methods. Strict adherence to universal precautions along with isolating HCV-infected dialysis patients might help to control disease spread in HD units.


Keywords: Hepatitis C virus, Chronic kidney disease, Hemodialysis, ELISA, Seroprevalance, Blood transfusion.
Download this article as Download

How to cite this article:

Nirmaladevi Somsundaram and Vidhya Rani, R. 2017. Seroprevalence of Hepatitis C Virus Infection among Chronic Kidney Disease Patients on Maintenance Hemodialysis in a Tertiary Care HospitalInt.J.Curr.Microbiol.App.Sci. 6(7): 1416-1420. doi: https://doi.org/10.20546/ijcmas.2017.607.169