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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 1056-1061
DOI: https://doi.org/10.20546/ijcmas.2017.607.127


Evaluation of Acute Physiology and Chronic Health Evaluation Score II in Acinetobacter baumannii Infection/Colonization and its Antimicrobial Resistance Profile in Kanpur, India
Nidhi Pal and R. Sujatha*
Department of Microbiology, Rama Medical College and Research Centre, Kanpur, India
*Corresponding author
Abstract:

Acute Physiology and Chronic Health Evaluation Score II (APACHEII) is one of the well-known scoring systems that is used to rule out severity of illness and Acinetobacter baumannii causes severe morbidity especially in ICU. The aim of this study is to evaluate APACHE II score in A. baumannii infected or colonized patients and find out the antimicrobial resistant pattern of isolates. In this case control study, clinical details were recorded among patients admitted to ICU. All the clinical samples like tips (endotraceal aspirates, tips, central line tips, and catheters tips), aspirates, blood, urine, fluid and pus were collected. A. baumannii and other isolates (infection or colonizer) were identified by different biochemical tests. All the clinical details were recorded to calculate APACHE II score. Antimicrobial resistance pattern was performed by disk diffusion method and resistant pattern were analysed according to CLSI guideline 2016. Total of 34 A. baumannii was isolated from critically ill patients. Clinically and microbiologically analyzed that 20 A. baumannii caused infections and rest 14 was isolated as a colonizer. Mean APACHE II Score was 23.94±3.78. While Mean APACHE II score of control cases were 20.01±4.11. A. baumannii causing infections were highly resistant. They showed 100% sensitivity against polymyxins only and 79.4% resistant for imipenem. But colonizers showed better sensitive for amikacin also. APACHE II Score can be a useful tool to predict A. baumannii infections. All the isolated Acinetobacter were highly resistant isolates which restrict the treatment options so it is very essential to treat patients by following all the infection control practices and provide more attention to patients with high APACHE II Score.


Keywords: APACHE II Score, Acinetobacter baumannii, Mortality, Resistance pattern.
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How to cite this article:

Nidhi Pal and Sujatha, R. 2017. Evaluation of Acute Physiology and Chronic Health Evaluation Score II in Acinetobacter baumannii Infection/Colonization and its Antimicrobial Resistance Profile in Kanpur, India.Int.J.Curr.Microbiol.App.Sci. 6(7): 1056-1061. doi: https://doi.org/10.20546/ijcmas.2017.607.127