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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:4, April, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(4): 84-90
DOI: http://dx.doi.org/10.20546/ijcmas.2016.504.012


Bacteriological Profile of Patients with AECOPD- Hospital Based Study
M.F. Aleemullah1*, V.Krishnamurthy2, M.Harish3 and C.Arshad Akeel4
1Department of Microbiology, Madha Medical College and Research Institute, Chennai, India
2Senior Consultant, Rheumatologist, Chennai Meenakshi Multi Speciality hospital Ltd, India
3Respiratory & Chest Physician, Chennai Meenakshi Multi Speciality Hospital Ltd, India
4Senior Consultant physician, Apollo Hospital, Chennai, India
*Corresponding author
Abstract:

COPD is defined as a disease state characterized by airflow limitation that is not fully reversible. The airflow limitation is usually both progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases. Exacerbations, mostly of bacterial, are a frequent cause of morbidity in COPD patients. A total of 148 sputum samples were collected from AECOPD patients. All collected sputum samples were subjected to standard microbiological procedures. Out of 148 sputum samples, growth of pathogenic organisms was obtained in 109 (73.65%) sputum samples. Gram negative organisms were isolated predominantly 68(62.39%). While Gram positive organisms accounted for 41(37.61%). Haemophilus influenzae 38(34.86) was the predominant bacteria isolated followed by Streptococcus pneumonia 25(22.94). Eight patients had  positive mycobacterial sputum culture on Lowenstien Jensen medium. Majority of isolates were sensitive to piperacillin/ tazobactum followed by amikacin. H. influenzae was the commonest bacterium isolated predominantly. Piperacillin/ tazobactum and amikacin were the most active antibacterial agents in our study. It is essential to screen for sputum AFB in endemic areas of tuberculosis.


Keywords: Haemophilus influenza, Chronic obstructive pulmonary disease,Tuberculosis.

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How to cite this article:

M.F. Aleemullah, V. Krishnamurthy, M.Harish and C. Arshad Akeel. 2016. Bacteriological Profile of Patients with AECOPD- Hospital Based StudyInt.J.Curr.Microbiol.App.Sci. 5(4): 84-90. doi: http://dx.doi.org/10.20546/ijcmas.2016.504.012
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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