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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(7): 386-396
DOI: https://doi.org/10.20546/ijcmas.2017.607.046


Characterization and Antibiogram of Klebsiellae Isolated From Clinical Samples
A. Asha*, Vimal Kumar Karnaker and Rekha Rai
Department of Microbiology, KS Hegde Medical Academy, Deralakatte, Mangalore-575018, Karnataka, India
*Corresponding author
Abstract:

Klebsiella spp exhibits an increased antimicrobial resistance by producing Extended Spectrum Beta Lactamases (ESBL) and Carbapenamases. Studying their resistance pattern will help in appropriate use of antibiotics and infection control. Aim of the study is to characterize Klebsiellae, to determine their antibiogram by disc diffusion, phenotypic detection of ESBL and carbapenemase. The study was conducted in the Department of Microbiology, K.S. Hegde Medical Academy, on the isolates of Klebsiella from samples of exudates, blood, CSF, body fluids, sputum and urine from October 2014 to April 2016. Klebsiellae were characterized and antibiotic susceptibility testing, phenotypic tests for ESBL and Carbapenemase production were done as per CLSI guidelines. Amongst 509 Klebsiella isolates, 93.3% were Klebsiella pneumoniae and 6.6% were Klebsiella oxytoca. Maximum susceptibility was to Meropenem (76.6%), Imipenem (75.83%). Maximum resistance (68.5% - 69.5%) was to the third generation Cephalosporins. Multi drug resistant Klebsiella comprised 28%, ESBL producers were 53.83% and 12.3% were Carbapenamase producers. Monitoring the ESBL and Carbapenamase production, for an effective antibiotic policy prevents MDR Klebsiellae and isolation by strict infection control prevents outbreaks.


Keywords: Industrialization, Industrial affected Soil, Heavy metals, Metal toxicity, Di - acid mixture.
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How to cite this article:

Asha A. Vimal Kumar Karnaker and Rekha Rai. 2017. Characterization and Antibiogram of Klebsiellae Isolated from Clinical Samples.Int.J.Curr.Microbiol.App.Sci. 6(7): 386-396. doi: https://doi.org/10.20546/ijcmas.2017.607.046