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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(6): 1194-1200
DOI: https://doi.org/10.20546/ijcmas.2017.606.138


Inflamosomes as Activated Molecular Platform for Engagement of Innate Immune Defences
Shubhangi Warke, Sumedha Bobade*, D.R. Kalorey and V.C. Ingle
Nagpur Veterinary College, Maharashtra Animal and Fishery Sciences University, Nagpur, India
*Corresponding author
Abstract:

Traditionally, innate immunity is first line of defence. These cells use multiprotein complexes called inflammasomes to produce proteins known as cytokines. The innate immune system plays a crucial role in the rapid recognition and elimination of invading microbes. The inflammasomes are large multiprotein complexes scaffolded by cytosolic pattern recognition receptors (PRRs) that form an important part of the innate immune system. In this review focus on relevant aspects concerning critical role of inflamosomes in mediating host defence, emerging links between the inflammasome and pyroptosis and autophagy, inflamosomes as design effective, safe adjuvants in the future has been discussed.


Keywords: DAMP, NLRC, NOD, PPR, TLR.
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How to cite this article:

Shubhangi Warke, Sumedha Bobade, D.R. Kalorey and Ingle, V.C. 2017. Inflamosomes as Activated Molecular Platform for Engagement of Innate Immune Defences.Int.J.Curr.Microbiol.App.Sci. 6(6): 1194-1200. doi: https://doi.org/10.20546/ijcmas.2017.606.138