National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Oral diseases are among the major public health problems and the most common of chronic diseases that affect mankind. Essential oils could serve as an important natural alternative to prevent microbial growth in oral infection diseases. This study was undertaken to determine the in vitro anticariogenic activities of 11 essential oils against dental pathogenic bacteria (Staphylococcus aureus, Streptococcus mutans and Streptococcus pyogenes) and fungi (Candida albicans and Candida parapsilosis) using agar well diffusion method, followed by determination of MIC. Most of the tested essential oils exhibited anticariogenic activity against all tested microbes. 16 formulations were made using them Formulations 10 and 13 showing good activity against C. albicans and C. parapsilosis. The formulations No. 10 and 13 showed strong antimicrobial activities with MIC ≥ 0.2mg/ml against C. albicans. Active components of oil were separated by TLC. Separation of the compounds of formulation 10 using TLC shows 5 different bands present. Among 5 bands, only 1 band was active against C. albicans. These materials can be served as an important natural alternative to prevent microbial growth in dental diseases. The prepared formulation also uses as natural alternative and also less expensive compared to the commercial product.
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