Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(6): 2611-2615
DOI: https://doi.org/10.20546/ijcmas.2017.606.312


Study of Nitrofurantoin Susceptibility in Bacterial Isolates from Patient of Urinary Tract Infection Attending Tertiary Care Centre
Saurabh Jain*, Saurabh G. Agarwal, Sanyogita Jain, Atul Rukadikar and Mamta Sarwaria
Department of Microbiology, Chirayu Medical College and Hospital Bhopal, MP, India
*Corresponding author
Abstract:

Increasing resistance rates of bacteria against standard antibiotics has become great problem for the treatment of UTI. To fight with this problem, an old drug Nitrofurantoin getting good attraction. Action at multiple sites and achieving levels in urine is the major strength of Nitrofurantoin as well as tolerated orally well and Side-effects are very less. Methodology: Study was conducted in Microbiology Department from April 2016 to April 2017. Urine samples were collected from patient admitted in various wards and attending O.P.D. and transport to laboratory. Every urine specimen received in the Microbiology laboratory was processed according to the recommended procedures for the isolation and identification of bacterial isolates. Bacteria were identified by colony morphology, gram staining and biochemical test from the primary isolation plates. Antibiotic susceptibility testing done for each isolates by DDT of Kirby Bauer on Muller Hinton Agar according to CLSI guideline. 357 urinary isolates were recovered with significant count in study period. E. coli 213 (59.66%) was the commonest organism isolated followed by Klebsiella pneumoniae 46 (12.89%), Enterococcus spp 33 (9.24%). Nitrofurantoin susceptibility in our study for E. coli was 72.3%, Klebsiella spp. 30.6%, Enterococcus 69.71%, Staphylococcus aureus 85.71%, Enterobacter 60 % and CONS 100%. However Mariraj et al., (2016) found 80-90% susceptibility for all urinary isolates and Rajesh et al., (2010) found E. coli was 82%, Klebsiella spp. 92 %, Enterococcus 00.00%. In the present era of antibiotic resistance urinary isolates show very good susceptibility for nitrofurantoin as compare to other commonly use antibiotic for treatment.


Keywords: Nitrofurantoin, Urinary Tract Infection, Antibiotic susceptibility, E. coli.
Download this article as Download

How to cite this article:

Saurabh Jain, Saurabh G. Agarwal,  Sanyogita Jain, Atul Rukadikar and Mamta Sarwaria. 2017. Study of Nitrofurantoin Susceptibility in Bacterial Isolates from Patient of Urinary Tract Infection Attending Tertiary Care Centre.Int.J.Curr.Microbiol.App.Sci. 6(6): 2611-2615. doi: https://doi.org/10.20546/ijcmas.2017.606.312