National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The estimation of G6PD deficiency (G6PDd) is an important aspect in the current situation of malaria elimination which requires use of primaquine to prevent transmission of P. falciparum and relapse of P. vivax. Long term use of primaquine can induce acute hemolytic anemia in G6PD deficient cases. A very little information is available about the prevalence of G6PDd among the malaria positive cases from India. The present study was designed to evaluate the G6PDd among the malaria positive patients attending the Calcutta School of Tropical Medicine. A total of 583 blood samples were collected from diagnosed malaria cases. G6PDd was estimated by Dichloro-phenol-indophenol (DCIP) decolorizing test. The mean age of recruited patients was 28.6 years ranging from 4-70 years. Out of 583 patients tested, 8 (1.37%) were found to be G6PD deficient. G6PDd was more prevalent in P. vivax infected patients (2.3%) than the P. falciparum (0.4%) (P-value = 0.0401). G6PD deficiency was more prevalent in females (2.06%) than in males (1.23%). The prevalence of G6PDd among the study population is low, but before the long term treatment of primaquine, G6PD deficiency test should be performed to avoid deaths due to primaquine induced acute hemolytic anemia.
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