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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(3): 738-744
DOI: http://dx.doi.org/10.20546/ijcmas.2016.503.086


Prevalence of G6PD Deficiency among the Malaria Patients in Urban Kolkata, India - A Clinic Based Study
Moytrey Chatterjee1, Swagata Ganguly1,2, Pabitra Saha1,3*, Dilip K. Bera5, Nandita Basu4 and Ardhendu K. Maji1
1Protozoology Unit, Department of Microbiology, Calcutta School of Tropical Medicine, 108,C.R. Avenue, Kolkata 700 073, India
2Department of Microbiology, NRS Medical College, 138 AJC Bose Road,Kolkata 700 014, India
3Department of Zoology, A. P. C. Roy Govt. College, Himachal Bihar, Matigara, Siliguri- 734 010, West Bengal, India
4Director, Calcutta School of Tropical Medicine, 108, C. R. Avenue, Kolkata 700 073, India
5Department of Microbiology, Calcutta School of Tropical Medicine, 108, C. R. Avenue, Kolkata 700 073, India
*Corresponding author
Abstract:

The estimation of G6PD deficiency (G6PDd) is an important aspect in the current situation of malaria elimination which requires use of primaquine to prevent transmission of P. falciparum and relapse of P. vivax. Long term use of primaquine can induce acute hemolytic anemia in G6PD deficient cases. A very little information is available about the prevalence of G6PDd among the malaria positive cases from India. The present study was designed to evaluate the G6PDd among the malaria positive patients attending the Calcutta School of Tropical Medicine. A total of 583 blood samples were collected from diagnosed malaria cases. G6PDd was estimated by Dichloro-phenol-indophenol (DCIP) decolorizing test. The mean age of recruited patients was 28.6 years ranging from 4-70 years. Out of 583 patients tested, 8 (1.37%) were found to be G6PD deficient. G6PDd was more prevalent in P. vivax infected patients (2.3%) than the P. falciparum (0.4%) (P-value = 0.0401). G6PD deficiency was more prevalent in females (2.06%) than in males (1.23%). The prevalence of G6PDd among the study population is low, but before the long term treatment of primaquine, G6PD deficiency test should be performed to avoid deaths due to primaquine induced acute hemolytic anemia.


Keywords: G6PD deficiency, Malaria,P. falciparum, P.vivax India.
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How to cite this article:

Moytrey Chatterjee, Swagata Ganguly, Pabitra Saha, Dilip K. Bera, Nandita Basu, and Ardhendu K. Maji. 2016. Prevalence of G6PD Deficiency Among the Malaria Patients in Urban Kolkata, India - A Clinic Based Study.Int.J.Curr.Microbiol.App.Sci. 5(3): 738-744. doi: http://dx.doi.org/10.20546/ijcmas.2016.503.086