National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Escherichia coli is the most common organism causing urinary tract infection (UTI). This organism has the ability to produce Extended Spectrum Beta Lactamases (ESBLs), which confer multiple drug resistance making urinary tract infection difficult to treat. So treatment of UTI requires constant updating of the antibiotic sensitivity profile. Objectives of this study were to detect prevalence of ESBL production among E. coli isolates causing urinary tract infection and to detect their antibiotic susceptibility pattern. A total of 400 consecutive, non-repetitive E. coli isolates were studied. Antimicrobial susceptibility test was performed using Kirby Bauer disk diffusion method. ESBL detection was done for all isolates according to latest CLSI criteria. Out of 400 E. coli isolate, 244(61%) were ESBL producers and 156(39%) were Non ESBL producers. The isolates were highly susceptible to imipenem (100%) and Piperacillin/Tazobactum (88.1%) and were least susceptible to Ampicillin (100%) and Cotrimoxazole (89.7%). This study demonstrate the importance of regular review of empirical antibiotic therapy for UTI in view of the evolving resistance of ESBL producing E. coli to commonly used antimicrobial agents.
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