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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(6): 279-286
DOI: https://doi.org/10.20546/ijcmas.2017.606.034


Isolation and Antibiotic Sensitivity Pattern of Extended Spectrum Beta Lactamases (ESBL) Producing Escherichia coli Isolated from Urinary Tract Infection
Ravindranath Gangane and Javeria Firdous*
Department of Microbiology, Mahadevappa Rampure Medical College, Kalaburagi, Karnataka, India
*Corresponding author
Abstract:

Escherichia coli is the most common organism causing urinary tract infection (UTI). This organism has the ability to produce Extended Spectrum Beta Lactamases (ESBLs), which confer multiple drug resistance making urinary tract infection difficult to treat. So treatment of UTI requires constant updating of the antibiotic sensitivity profile. Objectives of this study were to detect prevalence of ESBL production among E. coli isolates causing urinary tract infection and to detect their antibiotic susceptibility pattern. A total of 400 consecutive, non-repetitive E. coli isolates were studied. Antimicrobial susceptibility test was performed using Kirby Bauer disk diffusion method. ESBL detection was done for all isolates according to latest CLSI criteria. Out of 400 E. coli isolate, 244(61%) were ESBL producers and 156(39%) were Non ESBL producers. The isolates were highly susceptible to imipenem (100%) and Piperacillin/Tazobactum (88.1%) and were least susceptible to Ampicillin (100%) and Cotrimoxazole (89.7%). This study demonstrate the importance of regular review of empirical antibiotic therapy for UTI in view of the evolving resistance of ESBL producing E. coli to commonly used antimicrobial agents.


Keywords: E. coli, UTI, ESBL, Kirby Bauer disk diffusion method, CLSI.
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How to cite this article:

Ravindranath Gangane and Javeria Firdous. 2017. Isolation and Antibiotic Sensitivity Pattern of Extended Spectrum Beta Lactamases (ESBL) Producing Escherichia coli Isolated from Urinary Tract Infection.Int.J.Curr.Microbiol.App.Sci. 6(6): 279-286. doi: https://doi.org/10.20546/ijcmas.2017.606.034