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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(5): 2866-2873
DOI: https://doi.org/10.20546/ijcmas.2017.605.326


Aerobic Bacterial Profile and Antimicrobial Susceptibility Pattern of Pus Isolates in a Tertiary Care Hospital in Hadoti Region
Sarita Rawat*, Naveen Saxena and Pooja Jain
MBS Hospital, GMC, Kota, Rajasthan, India
*Corresponding author
Abstract:

Pyogenic infections are one of the major complications of surgery and trauma. The emerging drug resistance among microorganism increases both morbidity as well as mortality in association with such infections. Thus, selection of appropriate antibiotics and its rational use plays a key role in prevention as well as treatment of these infections. The indiscriminate use of antibiotics is one of the leading cause of emergence of drug resistant pathogens. Knowledge of etiological agents of infections and their resistance pattern is necessary to stop the continued emergence of resistance. Thus, this study will help the clinician with the tool to provide safe and effective empirical therapy. The aim of the study was to determine the commonly encountered pathogens in pus samples along with their antibiogram. This study was conducted from August 2015 to January 2016 in central lab, MBS hospital kota. Pus samples received for diagnostic microbiology was processed and identified by standard protocols. Antibiotic susceptibility test was done by Kirby Bauer disc diffusion method. Out of 150 pus samples received for culture and sensitivity in the microbiology central laboratory, 120 (80%) cases yielded positive culture while 30 (20%) cases had no growth. Among the 120 culture positive pus samples, 105 yielded pure bacterial isolates and 15 yielded mixed infection. E. coli was the most common isolates followed by Staphylococcus aureus, K. pneumoniae, Pseudomonas aeruginosa, Enterococcus spp and Proteus. Among the Gram positive isolates vancomycin, linezolid and tetracycline were the most susceptible drugs whereas among the Gram negative isolates, the most susceptible drugs were meropenem, amikacin and tetracycline. Whereas among nonfermenters most effective drug was polymyxin B followed by piperacillin- tazobactam, amikacin and meropenem. Antimicrobial resistance poses challenge in treating pyogenic infections. So appropriate and rational use of antibiotic is important to avoid emergence of multidrug resistant strains.


Keywords: Antimicrobial Susceptibility and resistance, pus samples
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How to cite this article:

Sarita Rawat, Naveen Saxena, Pooja Jain. 2016. Aerobic Bacterial Profile and Antimicrobial Susceptibility Pattern of Pus Isolates in a Tertiary Care Hospital in Hadoti region.Int.J.Curr.Microbiol.App.Sci. 6(5): 2866-2873. doi: https://doi.org/10.20546/ijcmas.2017.605.326