National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Urinary Tract Infection (UTI) is one of the most common infections observed in clinical practice among the community and hospitalized patients. Since the pattern of susceptibility is constantly changing, monitoring the changing trends has become more important. It provides information of the pathogenic organisms isolated from patients as well as assists in choosing the appropriate antimicrobial therapy. This retrospective study aims to analyze various uropathogens and their antimicrobial susceptibility pattern which would assist in selecting the most appropriate antibiotic therapy and for treatment of UTI in a tertiary care hospital. 700 urine isolates were studied retrospectively from November 2016 to January2017 which were cultured on to Blood agar and MacConkey agar plate. The plates that showed colonies >105 were considered significant and were identified by standard biochemical tests & sensitivity of the organisms was performed by Kirby – Bauer method on Mueller Hinton agar. Out of the 700 samples processed,48.6% (340) gave positive urine culture, of which 73 (61.86%) were Escherichia coli 69% (107), Klebsiella spp.,11.6%(18), Proteus spp., 9.7%(15), pseudomonas spp.,8.4% (13), Acinetobacter spp.,1.3%(2) and Coagulase Negative Staphylococcus(CONS) 67% (130), Candida spp.,24.7%(48), Enterococci spp., 8.3%(16) respectively. Susceptibility patterns of each isolates have been determined. Resistance pattern observed was ESBL was about 87%, MBL 8% and AmpC7% among the Gram negative organisms. This study discourages the indiscriminate use of antibiotics which in turn would prevent further development of bacterial drug resistance. For this, a proper knowledge of susceptibility pattern of uropathogens is necessary before prescribing empirical antibiotic therapy.
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