National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Coagulase-negative staphylococci (CNS) are a main cause of nosocomial infection. The main purpose of this study was to determination of frequency of CNS isolates in in hospitalized patients and their susceptibility pattern to antimicrobial agents. During 11 months study, 147CNS clinical isolates were recovered from hospitalized patients in NMC & hospital Nellore south India. The age of patients was 10 t0 70yrs. In vitro susceptibility of isolates to 14 antimicrobial agents – ampicilin, oxacillin, cefexime. azithromycin, oflaxacin, clindamycin, amikacim, tegycyclin, vancomycin, tegycyclin. vancomycin, amoxicillin with clavalinic acid, Tycarcillin with clavalanic acid, piperacillin with tazobactum. sporflaxacin and linezolid was performed by Kirby-Bauer’s Disk diffusion method according to Clinical and Laboratory Standards Institute (CLSl) criteria. Out of 147 patients were infected with CNS during study periodin different clinical specimens includes fifty four (36.73%) were isolated from urine. Fifty three (36.05%.) from the pus 21(14.29%) from sputum, 19(12.93%) from blood samples. Most of CNS isolates were sensitive to linezolid 134(91.16%), tegycyclin 130(88.44%) and vancomycin 123(83.67%). Highest resistance seen cefexime 96(65.31), azythromycin 79(53.74%), ampicillin 76(51.70%) Multi-drug resistant CNS with reduced susceptibility to linezolid, vancomycin emerging pathogens of clinical concern. Monitoring of antibiotic resistance with attention to multi-resistant profile and aware to practitioners in the field is necessary.
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