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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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Original Research Articles                      Volume : 12, Issue:3, March, 2023

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2023.12(3): 21-28
DOI: https://doi.org/10.20546/ijcmas.2023.1203.003


Prevalence of Hepatitis B Virus Infection in Antenatal Women in a Tertiary Care Hospital
D. Gayathri Devi, Rajesh Sengodan*, V. Aruna and S. Nirmala
Govt.Mohan Kumaramangalam Medical College Hospital, Salem, Tamil Nadu, India
*Corresponding author
Abstract:

Background: Hepatitis B virus (HBV) infection is a major global health problem. It causes chronic infection and high risk of mortality from cirrhosis and liver cancer. Antenatal women with HBV infection may transmit the virus vertically to neonates during pregnancy or delivery. Hepatitis B surface antigen (HBsAg) is the first serological marker of HBV infection. Screening of antenatal mothers for HBsAg would help in at risk of transmitting the infection to infants. Hence this study was conducted to determine the prevalence of Hepatitis B infection in antenatal women. Aims and Objective: To determine the prevalence of HBsAg positivity in antenatal women. Materials and methods: This was a descriptive study done at Department of Diagnostic Microbiology, Government Mohan Kumaramangalam Medical College, Salem. This study was carried out among 100 antenatal mothers attending Obstetric department from July 2022 to September 2022. Blood specimen was collected from the women were tested for the presence of HBsAg using Enzyme Linked Immuno Sorbent Assay (ELISA). Results: It was observed that the highest number of antenatal mothers attending Obstetric department was in the age group of 21 to 30 years (51%). 43% of the antenatal women were multigravidae and 50% of women visited during the last trimester. It was found that 2(2%) of 100 antenatal mothers were positive for Hepatitis B surface antigen. Conclusion: Screening of antenatal women for HBV infection is of significant help to decrease the risk of vertical transmission to the newborn babies born to HBsAg positive mothers by giving timely post exposure prophylaxis and continuous followup. This would help in decreasing the morbidity and carrier state.


Keywords: HBsAg, Antenatal mothers, Vertical transmission, Post exposure prophylaxis

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How to cite this article:

Gayathri Devi, D., Rajesh Sengodan, V. Aruna and Nirmala, S. 2023. Prevalence of Hepatitis B Virus Infection in Antenatal Women in A Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 12(3): 21-28. doi: https://doi.org/10.20546/ijcmas.2023.1203.003
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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