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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 12, Issue:2, February, 2023

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2023.12(2): 1-7
DOI: https://doi.org/10.20546/ijcmas.2023.1202.001


The Role of IL-6 and IL-17 in Patients with Toxoplasmosis in Baghdad, Iraq
Mohammed Jasim Shaker* and Rawaa Abdulkhaleq Hussein
Department of Microbiology, College of Medicine, University of Diyala, Diyala, Iraq
*Corresponding author
Abstract:

Toxoplasma gondii is one of the most frequent human zoonosis, infecting around a third of the world's population. Aim of the study: The present study was carried out to evaluate the role of serum level of IL-6 and IL-17 in aborted women infection with Toxoplasma gondii. Sixty aborted women (patients) and also thirty apparently healthy women as a control group were involved in present study. The women were between 20 to 43 years of age, all were attend Medical Centers in Baghdad city, during the period from 1st October 2021 till 15th August 2022. The interleukins that were measured by ELISA test were Interleukin-6(IL6), and Interleukin-17(IL17). The study showed a high significant increase in serum level of IL-6 and IL-17 in patients (27.45 ±3.19,218.02 ±23.97Pg/ml) respectively, when compared with serum levels in control group (9.52 ±0.96pg/ml, 24.31 ±2.35pg/ml) respectively, The role of IL-6 and IL-17 in the immune response against toxoplasmosis was studied, it was found that there was a concomitant increase of IL-6 with the increase of IL-17. A significant elevation levels of IL-6 and IL-17 in aborted women with toxoplasmosis in comparison with healthy women. That demonstrates the significance of these interleukins in stimulating or impressing immune response and resistance to toxoplasmosis.


Keywords: Aborted women, IL-6 and IL-17, Toxoplasma gondii

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How to cite this article:

Mohammed Jasim Shaker and Rawaa Abdulkhaleq Hussein. 2023. The Role of IL-6 and IL-17 in Patients with Toxoplasmosis in Baghdad, Iraq.

Int.J.Curr.Microbiol.App.Sci. 12(2): 1-7. doi: https://doi.org/10.20546/ijcmas.2023.1202.001
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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