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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(5): 747-752
DOI: https://doi.org/10.20546/ijcmas.2017.605.084


Evaluation of CD4 Cell Count and its Associating Factors - In HIV-TB Co-Infection
Jyotsna Chandwani*, Priyanka Soni, Geeta Parihar and Chandrakant Meena
Department of Microbiology, JLN Medical College and Hospital, Ajmer, India
*Corresponding author
Abstract:

HIV/AIDS is a serious life threatening disease. The interaction of TB & HIV is two-fold, with TB being the leading cause of death among HIV infected patients. A decrease in CD4 count in HIV-TB co-infection, leads to an increase in morbidity and mortality. So this study was done to evaluate the CD4 cell count and its associating factors in HIV-TB co infection to estimate their immune status. This was a retrospective study, conducted in Jawahar Lal Nehru Medical College & associated group of Hospitals, Ajmer, Rajasthan, India. A total of 289 HIV-TB co- infected patients attending ART centre, from January 2015 to December 2016 were enrolled in this study. CD4 count was done by BD FACS count. Statistical analysis was performed with the SPSS. A total of 289 HIV/AIDS sero-positive cases on ART having co-infection of TB were included in the study. In our study EPTB patients160 (55.36%) were higher in number as compared to PTB patients106 (44.64%). In majority of cases CD4 count was <200cells/µl which were 171 (59.17). A significant correlation was observed with age & CD4 count. Extra-pulmonary & sputum negative pulmonary HIV-TB patients outnumbered the sputum positive HIV-TB co-infected patients, which concludes that a newer & better test is required.


Keywords: CD4 count, extra-pulmonary TB, pulmonary TB, HIV.
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How to cite this article:

Jyotsna Chandwani, Priyanka Soni, Geeta Parihar and Chandrakant Meena. 2017. Evaluation of CD4 Cell Count and its Associating Factors - In HIV-TB Co-Infection.Int.J.Curr.Microbiol.App.Sci. 6(5): 747-752. doi: https://doi.org/10.20546/ijcmas.2017.605.084