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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(5): 202-211
DOI: https://doi.org/10.20546/ijcmas.2017.605.024


Egyptian Propolis 12: Influence of Propolis on Cytokines of Toxoplasma gondii Infected Rats
Ahmed G. Hegazi1*, Fayez M. Al Guthami2, Ahmed F.M. Al Gethami2 and Ashraf M. Barakat1
1National Research Centre, Dokki, Giza, Egypt
2Al Guthami Foundation, Saudi Arabia
*Corresponding author
Abstract:

This investigation conducted to study the influence of Egyptian propolis on immunological responses with special reference to cytokine levels of infected rats with Toxoplasma gondii and treated with 0.1 ml propolis day after day till the end of the experiment (28 days). Immune response of rats was evaluated weekly. The results revealed that the propolis was the highest in the toxoplasma antibodies titer when comparing with control group from the 2nd week to the end of experiment. Serum level of cytokines was consistently higher in the treated and propolis infected rats compared with controls. Serum cytokine levels of rats after infection with T. gondii showed significantly reduced levels of tumor necrosis factor-α (TNFα), IL-1β and IL-6 levels if compared to those in infected control rats or propolis treated group.


Keywords: Toxoplasma gondii infection, Propolis, Cytokines.
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How to cite this article:

Ahmed G. Hegazi, Fayez M. Al Guthami, Ahmed F.M. Al Gethami and Ashraf M. Barakat. 2017. Egyptian Propolis 12: Influence of Propolis on Cytokines of Toxoplasma gondii Infected RatsInt.J.Curr.Microbiol.App.Sci. 6(5): 202-211. doi: https://doi.org/10.20546/ijcmas.2017.605.024