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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:5, May, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(5): 202-211
DOI: https://doi.org/10.20546/ijcmas.2017.605.024


Egyptian Propolis 12: Influence of Propolis on Cytokines of Toxoplasma gondii Infected Rats
Ahmed G. Hegazi1*, Fayez M. Al Guthami2, Ahmed F.M. Al Gethami2 and Ashraf M. Barakat1
1National Research Centre, Dokki, Giza, Egypt
2Al Guthami Foundation, Saudi Arabia
*Corresponding author
Abstract:

This investigation conducted to study the influence of Egyptian propolis on immunological responses with special reference to cytokine levels of infected rats with Toxoplasma gondii and treated with 0.1 ml propolis day after day till the end of the experiment (28 days). Immune response of rats was evaluated weekly. The results revealed that the propolis was the highest in the toxoplasma antibodies titer when comparing with control group from the 2nd week to the end of experiment. Serum level of cytokines was consistently higher in the treated and propolis infected rats compared with controls. Serum cytokine levels of rats after infection with T. gondii showed significantly reduced levels of tumor necrosis factor-α (TNFα), IL-1β and IL-6 levels if compared to those in infected control rats or propolis treated group.


Keywords: Toxoplasma gondii infection, Propolis, Cytokines.

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How to cite this article:

Ahmed G. Hegazi, Fayez M. Al Guthami, Ahmed F.M. Al Gethami and Ashraf M. Barakat. 2017. Egyptian Propolis 12: Influence of Propolis on Cytokines of Toxoplasma gondii Infected RatsInt.J.Curr.Microbiol.App.Sci. 6(5): 202-211. doi: https://doi.org/10.20546/ijcmas.2017.605.024
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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