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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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Original Research Articles                      Volume : 10, Issue:7, July, 2021

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2021.10(7): 422-426
DOI: https://doi.org/10.20546/ijcmas.2021.1007.046


Comparison of Bacillus Calmette Guerin (BCG) Vaccine and Mitomycin C as an Adjuvant Therapy after the Surgical Excision of Bovine Ocular Squamous Cell Carcinoma
N. Priyanka1*, B. N. Nagaraja2, N. Nagaraju3, D. R. Manjunathand B. R. Balapannavar5
1Department of Veterinary Surgery and Radiology, Veterinary College,KVAFSU, Bidar-585401, India
2Department of Veterinary Surgery and Radiology, Veterinary College,Bengaluru-560024, India
3Department of Veterinary Surgery and Radiology, Veterinary College, Gadag -571201, India
4Department of TVCC, Veterinary College, Hassan -573202, India
5Department of Veterinary Surgery and Radiology, Veterinary College,Hassan -573202, India
*Corresponding author
Abstract:

Ocular squamous cell carcinoma is the most common neoplasm of the eye in cattle. It is a primary neoplasm of epithelial origin which occurs in different ocular and periocular tissues. Bovine ocular squamous cell carcinoma (OSCC) also called “Cancer eye” represents the most economically important and malignant tumor among tumors affecting large animals. In group A six animals with third eyelid tumour after the surgical excision subjected to subcutaneous administration of BCG vaccine at 0, 5 and 15 day. In group B six animals with third eyelid tumour after surgical excision subjected to administration of Mitomycin C 0.04% topically on alternate weeks for two months as adjunctive therapy. All the animals observed for a follow up period of six months for recurrence of tumor.


Keywords: Bacillus Calmette- Guerin (BCG) vaccine, Bovine ocular squamous cell carcinoma and Mitomycin C

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How to cite this article:

Priyanka, N., B. N. Nagaraja, N. Nagaraju, D. R. Manjunath and Balapannavar, B. R. 2021. Comparison of Bacillus Calmette Guerin (BCG) Vaccine and Mitomycin C as an Adjuvant Therapy after the Surgical Excision of Bovine Ocular Squamous Cell Carcinoma.Int.J.Curr.Microbiol.App.Sci. 10(7): 422-426. doi: https://doi.org/10.20546/ijcmas.2021.1007.046
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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