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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2016 - IJCMAS--ICV 2016: 92.3 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2016: 92.3
Index Copernicus ICI Journals Master List 2016 - IJCMAS--ICV 2016: 92.3
For more details click here
journals IJCMAS
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(4): 2753-2765
DOI: https://doi.org/10.20546/ijcmas.2017.604.319


Bacteriological Investigation of Helicobacter pylori Infections in Patients with Gastric and Duodenal Ulcer
Haitham Refaay Mustafa Elshiekh1*, Amr M. Elrabat2, Ahamed M. Sultan3 and Mahmoud M. Zaky4
1Department of Microbiology, Faculty of Science, Al-Azhar University, Assiut, Egypt
2Department of Internal Medicine, Faculty of Medicine, Mansoura University, Egypt
3Department of General Surgery, Faculty of Medicine, Mansoura University, Egypt
4Department of Microbiology, Faculty of Science, Port Said University, Port Said, Egypt
*Corresponding author
Abstract:

pylori colonize all human populations worldwide. The risk of being colonized by H. pylori depends on geographic area, socioeconomic status and age, and initial colonization is thought to occur during early childhood. In developing countries the infection can be almost ubiquitous, whereas in industrialized countries H. pylori infect 30–50% of adults. H pylori response to both Clarithromycin and Metronidazole antibiotic sensitivity was giving the same figures. In respect to gender, 90.9 % of males and 88.2 % of females were sensitive to both antibiotics. Tetracycline antibiotic sensitivity was showing that 81.8 % of the males and 88.2 % of the females were sensitive to Tetracycline antibiotics. Amoxicillin antibiotic sensitivity was showing that, 81.8 % of the males and 70.6 % of the females were sensitive to Amoxicillin antibiotics. Finally Furazolidone antibiotic sensitivity was showing that, 100 % of the males and 76.5 % of the females were sensitive to Furazolidone antibiotics. Finally, females were more susceptible to H pylori infection than male. Stool antigen analysis was more sensitive than either gram stain or urease test but still not reaching 100 percent as biopsy culture do. H pylori are more sensitive to Clarithromycin and Metronidazole while, Amoxicillin show less sensitivity in response to H pylori infection. From the study we may recommend to detect H pylori infection using molecular biology technique for detection of H pylori gene to increase the sensitivity to H pylori infection diagnosis.


Keywords: pylori, Gastric and duodenal ulcer, Biopsy, Antibiotic sensitivity, Urease test.
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How to cite this article:

Haitham Refaay Mustafa Elshiekh, Amr M. Elrabat, Ahamed M. Sultan and Mahmoud M. Zaky. 2017. Bacteriological Investigation of Helicobacter pylori Infections in Patients with Gastric and Duodenal Ulcer.Int.J.Curr.Microbiol.App.Sci. 6(4): 2753-2765. doi: https://doi.org/10.20546/ijcmas.2017.604.319