National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
To determine the most effective vaccine against rabies infection in the vaccines who took different types of vaccines for dog bite in rural areas of Tuticorin and urban areas of Bangalore. All the blood samples collected post intramuscular vaccinations were tested by RFFIT (Rapid Fluorescent Focus Inhibition Test). A total of 100 blood samples from vaccines were collected twice on days (14, 28) from volunteers in the period between 2013-2016. A cohort of 25 vaccinees were assigned to four different types of rabies vaccines groups PCEV (Rabipur, India), PVRV (Verorab, France), HDCV (Mireux, France), PDEC (Vaxirab, India). Responses to four commercially available vaccines in India were compared namely PCEC, HDCV, PVRV, PDEV. Although all available types of vaccines had elicited the required minimum rabies virus neutralizing antibody RVNA (titers above 0.5 IU), the following vaccine Purified Vero Cell Vaccine PVRV elicited the maximum neutralizing antiviral antibodies in the vaccine recipients (vaccinees). However, no significant differences in the quantum of RVNA were observed in all groups.
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