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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2016 - IJCMAS--ICV 2016: 92.3 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2016: 92.3
Index Copernicus ICI Journals Master List 2016 - IJCMAS--ICV 2016: 92.3
For more details click here
journals IJCMAS
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(4): 2021-2028
DOI: https://doi.org/10.20546/ijcmas.2017.604.239


Studies of Anti-Diabetic Effect of Morinda citrifolia Fruit Juice on Alloxan Induced Diabetic Rat
Nitin D. Jadhav, Debi P. Mishra*, Abhinna K. Behera, Sudhir R. Rajurkar and Bhagirath V. Ballurkar
Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences, Parbhani, India
*Corresponding author
Abstract:

Diabetes is a metabolic disorder due to insufficiency of insulin (absolute/relative) and generally classified as IDDM and NIDDM. Present study was conducted to observe the anti-diabetic effect of Morinda citrifolia fruit juice. 48 wistar rats of either sex comprising of four groups were taken for the study. Three groups of 36 rats was induced diabetes with single i/p administration of 5% w/v of alloxan monohydrate in normal saline. One group was kept as healthy control (Group-I) and one as diabetic control (Group-II).For comparison of the effect of Morinda citrifolia fruit juice @ 2 mg/kg Bwt. (Group-IV) with normal standard drug i.e. metformin @ 100 mg/kg Bwt. (Group-III). All the treatments were given through oral route. Parameter studied were serum Glucose, Triglyceride, Total cholesterol, HDL, LDL and Haemoglobin at 1st, 14th, 28th days after commencement of treatment. After induction of diabetes serum glucose and triglyceride concentration increased and total cholesterol, HDL, LDL concentration decreased at statistically significant level where as there was no statistical change in haemoglobin level. The group treated with Morinda citrifolia fruit juice showed better result but the best result was obtained with the standard anti-diabetic drug.


Keywords: Anti-Diabetic, Morinda citrifolia, Fruit Juice, Alloxan Induced Diabetic Rat.
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How to cite this article:

Nitin D. Jadhav, Debi P. Mishra, Abhinna K. Behera, Sudhir R. Rajurkar and Bhagirath V. Ballurkar. 2017. Studies of Anti-Diabetic Effect of Morinda citrifolia Fruit Juice on Alloxan Induced Diabetic Rat.Int.J.Curr.Microbiol.App.Sci. 6(4): 2021-2028. doi: https://doi.org/10.20546/ijcmas.2017.604.239