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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(12): 183-188
DOI: https://doi.org/10.20546/ijcmas.2020.912.025


Comparison of Phenotypic Methods of Detection of Carbapenamases in a Tertiary Care Hospital, South India
M. Uma Maheswari*
Department of Microbiology, PSGIMSR, Coimbatore, India
*Corresponding author
Abstract:

Enterobacteriaceae are the most frequently isolated organisms from clinical specimens. Among them Escherichia coli and Klebsiella pneumoniae cause a wide variety of clinical infections. With the emergence of ESBLs, carbapenems became the drug of choice. During the past decade, there has been an emergence of carbapenems-resistant Enterobacteriaceae that produce carbapenamases. So detection of carbapenamase producing Enterobacteriaceae has become mandatory for effective treatment. Hundred isolates of Meropenam resistant Escherichia coli and Klebsiella pneumoniae were selected. Modified Hodge test, double disc synergy test, combined disc or Disc enhancement test and Carba Np Test were done for these resistant isolates among them. The sensitivity and specificity of Carba Np test was 100 % and better than Modified Hodge test, combined disc test and double disc synergy test. Thus carba Np test is more effective and easily adoptable method used to identify the carbapenamase producing organisms.


Keywords: Carbapenamase, Carba Np test
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How to cite this article:

Uma Maheswari, M. 2020. Comparison of Phenotypic Methods of Detection of Carbapenamases in a Tertiary Care Hospital, South India.Int.J.Curr.Microbiol.App.Sci. 9(12): 183-188. doi: https://doi.org/10.20546/ijcmas.2020.912.025