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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(3): 121-128
DOI: http://dx.doi.org/10.20546/ijcmas.2016.503.017


Resistance of Antimicrobial in Pseudomonas aeruginosa
Sheetal Sharma* and Preeti Srivastava
Department of Microbiology, NIMS Medical College & Hospital, Jaipur Rajasthan-303121, India
*Corresponding author
Abstract:

Increasing number of reports had documented the continued emergency of resistance among Pseudomonas aeruginosa strains to common antibiotics drug, world-wide. This study investigated the antimicrobial resistance patterns of P. aeruginosa clinical isolates from hospitalized patients. Ongoing surveillance of P. aeruginosa resistant against antimicrobial is fundamental to monitor trends in susceptibility patterns and appropriately guide clinicians in choosing empirical or directed therapy. This study was conducted from August 2015 to December 2015 in Department of Microbiology at NIMS Medical College & Hospital Jaipur, Rajasthan, India. One hundred twenty six isolates of P. aeruginosa were isolated from different clinical specimens and fully characterized by standard bacteriological procedures. Antimicrobial susceptibility pattern of each isolates was carried out by the Kirby-Bauer disk diffusion method as per CLSI guidelines. Majority of P. aeruginosa were isolated from Pus, Sputum, Urine specimens. The isolate pathogen shows resistance to Amikacin (18.45%), ciprofloxacin (31.74%) and Cefoperazone – sulbactam (36.50%). All the isolates were (100%) susceptible to Meropenem and Imipenem. The result confirmed the occurrence of drug resistance strains of P.aeruginosa. Meropenem, Imipenem, Amikacin, ciprofloxacin were found to be the most effective antimicrobial drugs. It therefore calls for a very judicious, rational treatment regimens prescription by the physicians to limit the further spread of antimicrobial resistance P. aeruginosa strains.


Keywords: Antimicrobial resistance, Pseudomonas aeruginosa, Clinical isolates.
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How to cite this article:

Sheetal Sharma and Preeti Srivastava. 2016. Resistance of Antimicrobial in Pseudomonas aeruginos.Int.J.Curr.Microbiol.App.Sci. 5(3): 121-128. doi: http://dx.doi.org/10.20546/ijcmas.2016.503.017