National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Increasing number of reports had documented the continued emergency of resistance among Pseudomonas aeruginosa strains to common antibiotics drug, world-wide. This study investigated the antimicrobial resistance patterns of P. aeruginosa clinical isolates from hospitalized patients. Ongoing surveillance of P. aeruginosa resistant against antimicrobial is fundamental to monitor trends in susceptibility patterns and appropriately guide clinicians in choosing empirical or directed therapy. This study was conducted from August 2015 to December 2015 in Department of Microbiology at NIMS Medical College & Hospital Jaipur, Rajasthan, India. One hundred twenty six isolates of P. aeruginosa were isolated from different clinical specimens and fully characterized by standard bacteriological procedures. Antimicrobial susceptibility pattern of each isolates was carried out by the Kirby-Bauer disk diffusion method as per CLSI guidelines. Majority of P. aeruginosa were isolated from Pus, Sputum, Urine specimens. The isolate pathogen shows resistance to Amikacin (18.45%), ciprofloxacin (31.74%) and Cefoperazone – sulbactam (36.50%). All the isolates were (100%) susceptible to Meropenem and Imipenem. The result confirmed the occurrence of drug resistance strains of P.aeruginosa. Meropenem, Imipenem, Amikacin, ciprofloxacin were found to be the most effective antimicrobial drugs. It therefore calls for a very judicious, rational treatment regimens prescription by the physicians to limit the further spread of antimicrobial resistance P. aeruginosa strains.
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