A field experiment was conducted during the kharif  season 2019 at Instructional-cum-Research Farm, Raj Mohini Devi College of Agriculture & Research Station, Ambikapur (C.G.) to evaluate the “Effect of herbicide against complex weed flora in transplanted rice,  under Northern hill zone of Chhattisgarh. The experiment was laid out in 10 treatments T₁ - Pretilachlor + Pyrazosulfuron (Ready mix) 769 g/ha as PE at 0-5 DAT, T₂ - Pretilachlor + Pyrazosulfuron (Ready mix) 922 g/ha as PE at 0-5 DAT, T₃ - Pretilachlor + Pyrazosulfuron (Ready mix) 615 g /ha as PE at 0-5 DAT, T₄ - Bensulfuron – methyl + Pretilachlor 660 g/ha as PE at 0-5 DAT, T₅ - Pyrazosulfuron – ethyl  15 g a.i / ha  as PE at 0-5 DAT, T₆ - Penoxsulam 35 g a.i / ha as a POE at 20-25 DAT, T₇ - Bispyribac – Na – Salt  25 g a.i/ ha  as a POE at 20-25 DAT, T₈ - Metsulfuron + Chlorimuron  4 g a.i. / ha  as a POE at 12-15 DAT, T₉ - Mechanical Weeding  at 20 & 40 DAT and T₁₀ - Weedy Check in RBD with three replications. The data indicated that significant higher growth parameter, yield attributes, yield and net return were obtained in mechanical weeding at 20 and 40 DAT, which was at par with treatment T₂ - Pretilachlor + Pyrazosulfuron (Ready mix) 922 g/ha as PE at 0-5 DAT, T₁ - Pretilachlor + Pyrazosulfuron (Ready mix) 769 g/ha, T₃ - Pretilachlor + Pyrazosulfuron (Ready mix) 615 g /ha and T₄ - Bensulfuron – methyl + Pretilachlor 660 g/ha. The economics analysis of yield also specified that treatment (T₉) mechanical weeding at 20 and 40 DAT recorded maximum net return and B:C ratio and which was at par with T₂ - Pretilachlor + Pyrazosulfuron (Ready mix) 922 g/ha as PE at 0-5 DAT, T₁ - Pretilachlor + Pyrazosulfuron (Ready mix) 769 g/ha, T₃ - Pretilachlor + Pyrazosulfuron (Ready mix) 615 g /ha and T₄ - Bensulfuron – methyl + Pretilachlor 660 g/ha but significantly superior over rest of the weed management treatments.

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