Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(10): 732-737
DOI: https://doi.org/10.20546/ijcmas.2020.910.088


Safety and Cross Protective Efficacy of Bacteriophage Lysate against Pasteurella multocida Infection in Mice
R. Durairajan*, Harshit Verma, Awadwsh Prajapati, Mohammmed Abbas, Mayank Rawat and Rishender Verma
Division of Biological Standardization, Indian Veterinary Research Institute (IVRI), Izatnagar, Dist. Bareilly, Uttar Pradesh, India
*Corresponding author
Abstract:

In this study established the methodology to isolate highly virulent bacteriophage and assessed the ability of this phage lysate to induce protection against wild-type challenge in mice and the natural host chickens. Subcutaneous administration of phage lysate to mice stimulated significant protection against Pasteurella multocida P52 and A1 serotypes. But, significantly phage lysate was able to induce protection through subcutaneous route against challenge with wild type Pasteurella multocida A1 serotype in chicken but not through intranasal administration of phage lysates


Keywords: Bacteriophage, Lytic, P. multocida type A, Isolation, Therapeutic application
Download this article as Download

How to cite this article:

Durairajan, R., Harshit Verma, Awadwsh Prajapati, Mohammmed Abbas, Mayank Rawat and Rishender Verma. 2020. Safety and Cross Protective Efficacy of Bacteriophage Lysate against Pasteurella multocida Infection in Mice.Int.J.Curr.Microbiol.App.Sci. 9(10): 732-737. doi: https://doi.org/10.20546/ijcmas.2020.910.088