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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2016 - IJCMAS--ICV 2016: 92.3 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2016: 92.3
Index Copernicus ICI Journals Master List 2016 - IJCMAS--ICV 2016: 92.3
For more details click here
journals IJCMAS
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(4): 460-465
DOI: https://doi.org/10.20546/ijcmas.2017.604.053


Screening of Carbapenem Resistant Enterobacteriaceae among Nosocomial Isolates: A Study from South India

T.V. Parimala*

Department of Microbiology, Shridevi Institute of Medical Sciences and Research Hospital, NH4, Sira road, Tumkuru, Karnataka, India
*Corresponding author
Abstract:

Enterobacteriaceae are inhabitants of the intestinal flora. Emergence of Carbapenem resistant Enterobacteriaceae (CRE) is a serious threat to public health. They rapidly acquire and transfer drug resistance genes through plasmids and transposons and spread to community via faeco-oral route. Hence the present study was done to know the magnitude of Carbapenem resistant Enterobacteriaceae in our hospital. This study was conducted in the department of Microbiology, SIMS and RH, Tumkuru during a period from May 2016 to October 2016. A total of 106 Enterobacteriaceae isolates were obtained by various clinical samples and from different department of the hospital. These isolates were screened for carbapenem resistance by disk diffusion method according to CLSI guidelines. Prevalence of CRE in our hospital is 44. 33%. Meropenem resistance (31. 13%) was higher than Imipenem resistance among CRE isolates. In this study, CRE is more common in male (50. 90%) patients. Majority of the sample is urine (55. 26%) and Maximum number of cases was from (51. 61%) OBG department. Most common species isolated was (63. 04%) Escherichia coli. Carbapenem resistant Enterobacteriaceae are more prevalent in our hospital. Hence use of carbapenem should be restricted to treat severe infections.


Keywords: Antibiotic resistance, Carbapenem, Enterobacteriaceae, Carbapenem resistant Enterobacteriaceae, Nosocomial isolates.
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How to cite this article:

Parimala, T.V. 2017. Screening of Carbapenem Resistant Enterobacteriaceae among Nosocomial Isolates: A study from South India.Int.J.Curr.Microbiol.App.Sci. 6(4): 460-465. doi: https://doi.org/10.20546/ijcmas.2017.604.053