National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Human Immunodeficiency Virus (HIV) has emerged as one of the most devastating human pandemics with significant morbidity and mortality. A plethora of physiological factors including haematological status, immunological response, renal and liver enzymes, sex hormones, vitamin and mineralogical status play significant role in determining the HIV infection progression and effect of anti-retro viral therapy (ART). The present study aims to investigate the overall physiological status in HIV infected individuals prior to ART. The study was conducted as a quasi-experimental study where HIV infected males and females at Stage I and III of HIV were assessed for their CD4 count, IL-6 content, biochemical, heamatological, immunological, hormonal and Vitamin D functions. Marked variations were noticed in majority of the study variables when compared with the standard defined values. Statistical significant results were obtained in case of total RBCs content and platelet distribution width (PDW) when compared within the disease stages along with increasing trend of few variables with disease progression. It is believed that baseline assessment of physiological parameters prior to treatment initiation will provide greater understanding of disease progression with better treatment outcomes.
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