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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2020.9(9): 1124-1138
DOI: https://doi.org/10.20546/ijcmas.2020.909.140


Physiological Status of HIV Infected Patients Pre ART
Vinay Malik1, Tung Vir Singh Arya1 and Aman Prakash Garg2
1LLRM Medical College and Hospital, Meerut, (UP), India 
2Shobhit Deemed University, Meerut, (UP), India
*Corresponding author
Abstract:

Human Immunodeficiency Virus (HIV) has emerged as one of the most devastating human pandemics with significant morbidity and mortality. A plethora of physiological factors including haematological status, immunological response, renal and liver enzymes, sex hormones, vitamin and mineralogical status play significant role in determining the HIV infection progression and effect of anti-retro viral therapy (ART). The present study aims to investigate the overall physiological status in HIV infected individuals prior to ART. The study was conducted as a quasi-experimental study where HIV infected males and females at Stage I and III of HIV were assessed for their CD4 count, IL-6 content, biochemical, heamatological, immunological, hormonal and Vitamin D functions. Marked variations were noticed in majority of the study variables when compared with the standard defined values. Statistical significant results were obtained in case of total RBCs content and platelet distribution width (PDW) when compared within the disease stages along with increasing trend of few variables with disease progression. It is believed that baseline assessment of physiological parameters prior to treatment initiation will provide greater understanding of disease progression with better treatment outcomes.


Keywords: HIV, Anti-Retroviral therapy, CD4 count, Liver damage, Renal function, Hematological status, IL-6, Sex hormones,Vitamin D
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How to cite this article:

Vinay Malik, Tung Vir Singh Arya and Aman Prakash Garg. 2020. Physiological Status of HIV Infected Patients Pre ART.Int.J.Curr.Microbiol.App.Sci. 9(9): 1124-1138. doi: https://doi.org/10.20546/ijcmas.2020.909.140