National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
ND is one of the most devastating diseases of the poultry industry. The disease was categorized as ‘notifiable’ owing to the immense economic losses caused to the poultry farmers. Wide host range is one major limiting factor in controlling the disease. While chicken, turkeys, doves, pigeons are highly susceptible, waterfowls such as ducks and geese are less susceptible and considered as natural reservoirs for lentogenic AAvV-1. We isolated an AAvV-1 strain from a goose raised in a mixed species poultry farm. Full length fusion gene sequence confirmed that the isolate belongs to genotype II of class II AAvV-1. Phylogenetic studies grouped the isolate with vaccine strain, Komarov. Twenty one day old chicken inoculated with this isolate were apparently healthy without any clinical signs. Minimal upregulation of proinflammatory, chemokine and apoptic cytokine levels was observed in the spleen of infected chicken. This study paved way for isolation of a low pathogenic strain of AAvV-1 from an apparently healthy water fowl. Further research is needed to evaluate the isolate as a vaccine candidate.
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