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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:4, April, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(4): 116-124
DOI: https://doi.org/10.20546/ijcmas.2017.604.014


Physiological and Biochemical Evaluation of Fomesafen Toxicity in Female Albino Wistar Rats
Alok Paliwal1, M.L. Agarwal1, K.M. Chacko1, Anurag Singh2, Abhishek Chauhan3 and Tanu Jindal3*
1Shriram Institute for Industrial Research, 19-University Road, Delhi-110007, India
2EM Facility, Department of Anatomy, AIIMS, Delhi-110029, India
3Amity Institute of Environmental Toxicology, Safety and Management, Amity University, Sector-125, Noida, Uttar Pradesh, India
*Corresponding author
Abstract:

Fomesafen is widely used as herbicide for weed control. Fomesafen have both foliar and soil activity. It mostly control broadleaves. Fomesafen is labeled for postemergence applications to soybeans, peanuts, and rice. Although bronzing or burning of soybean leaf tissue is evident after application, yield is rarely affected. The present study was designed to evaluate the effect of repeated exposure of Fomesafen (Herbicide) by oral gavage method on the blood biochemistry of female wistar rats. The study highlights the various changes in biochemical parameters of female wistar rats over repeated exposure by Fomesafen by oral route through gavage. Under the conditions of this study, the repeated oral administration of ‘Fomesafen technical’ in Female wistar rats at the dosage level of 50 mg/kg b.wt. for consecutive 90 days did not induce any observable toxic effects, alteration in blood biochemistry parameters when compared to its corresponding control group of animals.


Keywords: Herbicides, Fomesafen, Wistar rat, Blood biochemistry, Repeated exposure

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How to cite this article:

Alok Paliwal, M.L. Agarwal, K.M. Chacko, Anurag Singh, Abhishek Chauhan and Tanu Jindal. 2017. Physiological and Biochemical Evaluation of Fomesafen Toxicity in Female Albino Wistar RatsInt.J.Curr.Microbiol.App.Sci. 6(4): 116-124. doi: https://doi.org/10.20546/ijcmas.2017.604.014
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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