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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(1): 209-220
DOI: http://dx.doi.org/10.20546/ijcmas.2016.501.019


Oral Cancer Biomarkers - as Powerful Diagnostic and Prognostic Tools Int.J.Curr.Microbiol.App.Sci.2016.5(1): 209-220
Palak Ahuja
Department of Biotechnology, Faculty of Science, Jamia Hamdard, New Delhi-110062, India
*Corresponding author
Abstract:

Oral cancer, a complex multistage process, is predominant in the Southeast Asian countries, owing to increased consumption of smokeless tobacco, tobacco, alcohol and Human papilloma virus type 16 infection. Oral cancers tends to advance from the non-healing pre-malignant lesions, namely, leukoplakia, erythroplakia and oral sub-mucous fibrosis. However, the major challenge encountered is to predict which pre-cancerous lesion might transform into oral carcinoma, indicating the importance of protein based molecular markers or biomarkers. Several biomarkers, with diagnostic, prognostic and therapeutic value for oral carcinogenesis have been identified till date and this review focuses on the current understanding of the potential OSCC biomarkers, such as Endothelin 1, salivary transferrin, zinc finger protein 510, microRNA: miR-31 as well as cytokine biomarkers, including


Keywords: Oral cancer, OSCC, Premalignant lesion, Biomarkers, cytokines,
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How to cite this article:

Int.J.Curr.Microbiol.App.Sci. 5(1): 209-220. doi: http://dx.doi.org/10.20546/ijcmas.2016.501.019