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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(3): 2485-2495
DOI: https://doi.org/10.20546/ijcmas.2017.603.281


Antagonistic Activity of Biogenic TiO2 Nanoparticles against Staphylococcus aureus and Escherichia coli
Durairasu1, V. Indra1, N. Arunagirinathan2, J. Hemapriya3 and S. Vijayanand4*
1Department of Zoology, Presidency College, Chennai, Tamilnadu, India
2Department of Microbiology, Presidency College, Chennai, Tamilnadu, India
3Department of Microbiology, DKM College, Vellore, Tamilnadu, India
4Department of Biotechnology, Thiruvalluvar University, Vellore, Tamilnadu, India
 
*Corresponding author
Abstract:

Nanobiotechnology is an emerging field of science that utilizes nanobased systems for various biotechnological and biomedical applications. The synthesis of metal and metal oxide nanoparticles has attracted considerable attention, as they have high surface area and high fraction of atoms which is responsible for their fascinating properties such as antimicrobial, magnetic, electronic and catalytic activity. The antibacterial activities of TiO2 nanoparticles were studied in Staphylococcus aureus and Escherichia coli. Treatment of the bacterial cells with TiO2 NP’s resulted in the leakage of reducing sugars, proteins and reduced the activity of the respiratory chain dehydrogenases. In conclusion, the combined results suggested that TiO2 NP’s was found to damage the bacterial cell membrane and depress the activity of some vital enzymes which eventually led to the death of bacterial cells. Thus TiO2 NP’s could be used as an effective antibacterial material in the burgeoning field of Nanomedicine research with tremendous prospects for the improvement of combating human pathogens.


Keywords: Antibacterial Activity, Escherichia coli, Staphylococcus aureus, TiO2 nanoparticles.
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How to cite this article:

Durairasu, M., V. Indra, N. Arunagirinathan, J. Hemapriya and Vijayanand, S. 2017. Antagonistic Activity of Biogenic TiO2 Nanoparticles against Staphylococcus aureus and Escherichia coli.Int.J.Curr.Microbiol.App.Sci. 6(3): 2485-2495. doi: https://doi.org/10.20546/ijcmas.2017.603.281